Corynebacterium glutamicum as a Host for Synthesis and Export of d-Amino Acids

N Stäbler, T Oikawa, M Bott, L Eggeling - Journal of bacteriology, 2011 - Am Soc Microbiol
ABSTRACT A number of d-amino acids occur in nature, and there is growing interest in their
function and metabolism, as well as in their production and use. Here we use the well …

Export of amino acids and other solutes

L Eggeling - … of Corynebacterium glutamicum. CRC Press, Boca …, 2005 - books.google.com
After the discovery that Corynebacterium glutamicum can easily be influenced to excrete L-
glutamate, powerful producers were rapidly developed for this amino acid and for L-lysine …

Metabolic design in amino acid producing bacterium Corynebacterium glutamicum

H Sahm, L Eggeling, B Eikmanns… - FEMS Microbiology …, 1995 - academic.oup.com
Abstract The Gram-positive bacterium Corynebacterium glutamicum is used for the industrial
production of amino acids, eg of l-glutamate and l-lysine. In the last 10 years, genetic …

Functional analysis of sequences adjacent to dapE of Corynebacterium glutamicum reveals the presence of aroP, which encodes the aromatic amino acid transporter

A Wehrmann, S Morakkabati, R Krämer… - Journal of …, 1995 - Am Soc Microbiol
An initially nonclonable DNA locus close to a gene of L-lysine biosynthesis in
Corynebacterium glutamicum was analyzed in detail. Its stepwise cloning and its functional …

Expression control and specificity of the basic amino acid exporter LysE of Corynebacterium glutamicum

A Bellmann, M Vrljic, M Patek, H Sahm… - …, 2001 - microbiologyresearch.org
LysE of Corynebacterium glutamicum belongs to a large new superfamily of translocators
whose members are probably all involved in the export of small solutes. Here, the transcript …

Construction of L-lysine-, L-threonine-, and L-isoleucine-overproducing strains of Corynebacterium glutamicum.

H Sahm, L Eggeling, B Eikmanns… - Annals of the New York …, 1996 - europepmc.org
The gram-negative bacterium Corynebacterium glutamicum is used for the industrial
production of amino acids, for example, of L-glutamate and L-lysine. By cloning and …

Cometabolism of a Nongrowth Substrate: l-Serine Utilization by Corynebacterium glutamicum

R Netzer, P Peters-Wendisch, L Eggeling… - Applied and …, 2004 - Am Soc Microbiol
Despite its key position in central metabolism, l-serine does not support the growth of
Corynebacterium glutamicum. Nevertheless, during growth on glucose, l-serine is …

Unbalance of L-lysine flux in Corynebacterium glutamicum and its use for the isolation of excretion-defective mutants

M Vrljic, W Kronemeyer, H Sahm… - Journal of …, 1995 - Am Soc Microbiol
We found that the simple addition of L-methionine to the wild type of Corynebacterium
glutamicum results in excretion of the cellular building block L-lysine up to rates of 2.5 …

Activity of Exporters of Escherichia coli in Corynebacterium glutamicum, and Their Use to Increase L-Threonine Production

R Diesveld, N Tietze, O Fürst, A Reth, B Bathe… - Journal of molecular …, 2009 - karger.com
L-Threonine is an important biotechnological product and Corynebacterium glutamicum is
able to synthesize and accumulate this amino acid to high intracellular levels. We here use …

Metabolic Engineering of Corynebacterium glutamicum for l-Serine Production

P Peters-Wendisch, M Stolz, H Etterich… - Applied and …, 2005 - Am Soc Microbiol
Although l-serine proceeds in just three steps from the glycolytic intermediate 3-
phosphoglycerate, and as much as 8% of the carbon assimilated from glucose is directed …