Risk factors for cytomegalovirus viremia and disease developing after prophylaxis in high-risk solid-organ transplant recipients

RB Freeman, C Paya, MD Pescovitz, A Humar… - …, 2004 - journals.lww.com
Background. Cytomegalovirus (CMV) D+/R− solid-organ transplant (SOT) recipients carry
increased risk of developing CMV disease; however, other risk factors in these patients have …

ERADICATION OF CYTOMEGALOVIRUS REACTIVATION DISEASE USING HIGH-DOSE ACYCLOVIR AND TARGETED INTRAVENOUS GANCICLOVIR IN KIDNEY …

GK Shen, EJ Alfrey, CL Knoppel, DC Dafoe… - …, 1997 - journals.lww.com
Background The attack rate of cytomegalovirus (CMV) is over 50% in solid organ transplant
recipients at risk for primary CMV infection and in those receiving antilymphocyte antibody …

[HTML][HTML] The efficacy and safety of 200 days valganciclovir cytomegalovirus prophylaxis in high‐risk kidney transplant recipients

A Humar, Y Lebranchu, F Vincenti, EA Blumberg… - American Journal of …, 2010 - Elsevier
Late‐onset cytomegalovirus (CMV) disease is a significant problem with a standard 3‐month
prophylaxis regimen. This multicentre, double‐blind, randomized controlled trial compared …

Prevention of late-onset cytomegalovirus infection and disease in Donor-Positive/Recipient-Negative kidney transplant recipients using low-dose valganciclovir

K Nanmoku, T Shinzato, T Kubo, T Shimizu… - Transplantation …, 2018 - Elsevier
Background The main challenge with cytomegalovirus (CMV) prophylaxis in IgG donor-
positive/recipient-negative (D+/R–) kidney transplant recipients is late-onset CMV disease …

Efficacy and safety of valgancyclovir as preemptive therapy for the prevention of cytomegalovirus disease in solid organ transplant recipients

C Dı́az-Pedroche, C Lumbreras, P Del Valle… - Transplantation …, 2005 - Elsevier
We prospectively followed 70 CMV-seropositive solid organ transplant recipients to evaluate
the efficacy and safety of valganciclovir (VGCV) as preemptive therapy based on …

[PDF][PDF] Increased incidence of cytomegalovirus infection in high‐risk liver transplant recipients receiving valganciclovir prophylaxis versus ganciclovir prophylaxis

KT Shiley, LB Gasink, TD Barton… - Liver …, 2009 - Wiley Online Library
Optimal measures for the prevention of cytomegalovirus (CMV) in high‐risk orthotopic liver
transplant (OLT) patients are unknown. The charts of high‐risk OLT recipients with 12 …

Valganciclovir prophylaxis versus preemptive therapy in cytomegalovirus-positive renal allograft recipients: 1-year results of a randomized clinical trial

O Witzke, IA Hauser, M Bartels, G Wolf, H Wolters… - …, 2012 - journals.lww.com
Background. Cytomegalovirus (CMV) prevention can be achieved by prophylaxis or
preemptive therapy. We performed a prospective randomized trial to determine whether …

Low‐dose valganciclovir prophylaxis for cytomegalovirus in intermediate‐risk (R+) renal transplant recipients: Single‐center experience

S Khan, C Fischman, S Huprikar - Transplant Infectious …, 2017 - Wiley Online Library
Renal transplant recipients (RTR) who are seropositive for CMV (R+) are considered to be at
intermediate risk for CMV disease. Current guidelines recommend high‐dose valganciclovir …

[HTML][HTML] Prophylactic versus preemptive oral valganciclovir for the management of cytomegalovirus infection in adult renal transplant recipients

JA Khoury, GA Storch, DL Bohl, RM Schuessler… - American Journal of …, 2006 - Elsevier
Prophylaxis reduces cytomegalovirus (CMV) disease, but is associated with increased costs
and risks for side effects, viral resistance and late onset CMV disease. Preemptive therapy …

Randomized controlled trial of sequential intravenous and oral ganciclovir versus prolonged intravenous ganciclovir for long-term prophylaxis of cytomegalovirus …

DJ Winston, RW Busuttil - Transplantation, 2004 - journals.lww.com
Cytomegalovirus (CMV)-seronegative liver transplant recipients with CMV-seropositive
donors have the greatest risk for CMV disease. We performed a randomized, controlled trial …