Ambient particulate matter (PM) concentrations have been associated with mortality and
morbidity. Diesel exhaust particles (DEP) are present in ambient urban air PM. Coexisting …

Epidemiological studies have observed statistical associations between short-term exposure
to increased ambient particulate air pollution and increased hospital admissions, medication …

Long-term, repeated exposure to particles in air pollution increases the risk for chronic
respiratory diseases and cardiorespiratory mortality. The biological linkages remain poorly …

Several plausible mechanisms have been proposed to explain the adverse health effects of
particulate matter (PM) in polluted ambient air [1]. To date, experimental support has been …

Background Mechanisms of cardiovascular injuries from exposure to gas and particulate air
pollutants are unknown. Objective We sought to determine whether episodic exposure of …

Chronic airway inflammation, mucus hypersecretion, reversible airway constriction, and
bronchial hyperresponsiveness are important pathogenic features of asthma. We found that …

The problem of whether or not active oxygen species are involved in pulmonary injury by
diesel exhaust particles (DEP) was investigated. We found that DEP could produce …

Pulmonary responses to diesel exhaust particles (DEP) exposure are mediated through
enhanced production of reactive oxygen species (ROS) and nitric oxide (NO) by alveolar …

Pollution by particulates has consistently been associated with increased cardiorespiratory
morbidity and mortality. It has been suggested that ultrafine particles, of which diesel …

Exposure to diesel exhaust particles (DEP) is an environmental and occupational health
concern. This review examines the cellular actions of the organic and the particulate …