The role of lncRNA-mediated ceRNA regulatory networks in pancreatic cancer

J Xu, J Xu, X Liu, J Jiang - Cell death discovery, 2022 - nature.com
Abstract Non-coding RNAs (ncRNAs), which occupy the vast majority of human transcripts
are known for their inability to encode proteins. NcRNAs consist of a diverse range of RNA …

[HTML][HTML] Construction and analysis of dysregulated lncRNA-associated ceRNA network identified novel lncRNA biomarkers for early diagnosis of human pancreatic …

M Zhou, Z Diao, X Yue, Y Chen, H Zhao, L Cheng… - Oncotarget, 2016 - ncbi.nlm.nih.gov
It is increasing evidence that ceRNA activity of long non-coding RNAs (lncRNAs) played
critical roles in both normal physiology and tumorigenesis. However, functional roles and …

[HTML][HTML] LncRNAs in pancreatic cancer

X Huang, X Zhi, Y Gao, N Ta, H Jiang, J Zheng - Oncotarget, 2016 - ncbi.nlm.nih.gov
Pancreatic cancer (PC) is one of the most common causes of cancer-related death. The
underlying mechanism of PC is not completely understood at present. Studies in recent …

The emerging role of major regulatory RNAs in cancer control

X Dai, AC Kaushik, J Zhang - Frontiers in oncology, 2019 - frontiersin.org
Alterations and personal variations of RNA interactions have been mechanistically coupled
with disease etiology and phenotypical variations. RNA biomarkers, RNA mimics, and RNA …

The involvement of lncRNAs in the development and progression of pancreatic cancer

L Duguang, H Jin, Q Xiaowei, X Peng… - Cancer Biology & …, 2017 - Taylor & Francis
Pancreatic cancer is one of the most malignant tumors that are difficult to diagnose at its
early stage and there is no effective therapy. Recent studies uncovered that many non …

Integrated analysis of a ceRNA network reveals potential prognostic lncRNAs in gastric cancer

M Qi, B Yu, H Yu, F Li - Cancer medicine, 2020 - Wiley Online Library
Long noncoding RNAs (lncRNAs) have important biological functions as competing
endogenous RNAs (ceRNAs) in tumors, yet the functions and regulatory mechanisms of …

Comprehensive analysis of a ceRNA network reveals potential prognostic cytoplasmic lncRNAs involved in HCC progression

Y Bai, J Long, Z Liu, J Lin, H Huang… - Journal of cellular …, 2019 - Wiley Online Library
The aberrant expression of long noncoding RNAs (lncRNAs) has drawn increasing attention
in the field of hepatocellular carcinoma (HCC) biology. In the present study, we obtained the …

Role of cytoplasmic lncRNAs in regulating cancer signaling pathways

P Fu, X Zheng, X Fan, A Lin - Journal of Zhejiang University-SCIENCE B, 2019 - Springer
Cancer remains a serious healthcare problem despite significant improvements in early
detection and treatment approaches in the past few decades. Novel biomarkers for …

Long noncoding RNAs in cancer and therapeutic potential

A Renganathan, E Felley-Bosco - Long Non Coding RNA Biology, 2017 - Springer
Long noncoding RNAs (lncRNAs) are the major elements of the mammalian transcriptome
that is emerging as a central player controlling diverse cellular mechanisms. Most of the well …

[HTML][HTML] Role of long noncoding RNA-mediated competing endogenous RNA regulatory network in hepatocellular carcinoma

ZS Niu, WH Wang, XN Dong - World journal of gastroenterology, 2020 - ncbi.nlm.nih.gov
Long noncoding RNAs (lncRNAs) and microRNAs (miRNAs) are noncoding RNAs
(ncRNAs) that occupy over 90% of the human genome, and their main function is to directly …