Clostridioides difficile causes a range of debilitating intestinal symptoms that may be fatal. It
is particularly problematic as a hospital-acquired infection, causing significant costs to the …

Clostridioides difficile is one of the most important causes of healthcare-associated diarrhea.
The high incidence and recurrence rates of C. difficile infection, as well as its associated …

Oral vancomycin and metronidazole, though they are the therapeutic choice for
Clostridioides difficile infections (CDIs), also markedly disturb microbiota, leading to a …

Faecal microbiota transplantation (FMT) has emerged as a remarkably successful treatment
for recurrent Clostridioides difficile infection that cannot be cured with antibiotics alone …

Introduction The role of the gut microbiota in health and the pathogenesis of several
diseases has been highlighted in recent years. Even though the precise mechanisms …

Clostridioides difficile is a major cause of health‐care related infections and antibiotic‐
associated diarrhea. High recurrence rates following antibiotic treatment, along with the …

Faecal microbiota transplant (FMT) is now accepted as an effective treatment for
Clostridioides difficile infections. With the increasing number of FMT treatments and clinical …

New therapies to treat and prevent Clostridioides difficile infections (CDI) are needed. CDI
requires antibiotic therapy, but this can disrupt gut microbiomes and increase susceptibility …

While anti-C. difficile antibiotics theoretically target clostridial species, in relapsing CDI they
often fail to eradicate the organism because of the presence of resistant spores. Such …

Clostridioides difficile infection (CDI) has become an increasingly common infection both
within and outside of the hospital setting. The management of this infection has been …