Differential effect of erythropoietin and GM-CSF on megakaryocytopoiesis from primitive bone marrow cells in serum-free conditions

JE Cardier, CL Erickson-Miller, MJ Murphy Jr - Stem Cells, 1997 - academic.oup.com
In this study we have explored the effect of recombinant human erythropoietin (EPO) and
recombinant murine GM-CSF on megakaryocyte progenitors (colony forming units …

[HTML][HTML] An optimized system for studies of EPO-dependent murine pro-erythroblast development

D Zhang, MM Johnson, CP Miller, TJ Pircher… - Experimental …, 2001 - Elsevier
OBJECTIVE: Objectives were to develop new means to isolate useful numbers of primary
progenitor cells and to quantitatively assay the stepwise maturation of erythroblasts …

Interleukins and colony stimulating factors in human myeloid leukemia cell lines

HT Hassan, HG Drexler - Leukemia & lymphoma, 1995 - Taylor & Francis
The present review has summarized the expression, production and effects of the human
interleukins (IL) 1-11 and myelopoietic colony stimulating factors (CSF) in the established …

Identification of circulating CD31+CD45+ cell populations with the potential to differentiate into erythroid cells

MCG Monaco, D Maric, O Salvucci, CAL Passeri… - Stem Cell Research & …, 2021 - Springer
Erythro-myeloid progenitors (EMP) are found in a population of cells expressing CD31 and
CD45 markers (CD31+ CD45+). A recent study indicated that EMPs persist until adulthood …

GpIIb/IIIa+ subpopulation of rat megakaryocyte progenitor cells exhibits high responsiveness to human thrombopoietin.

T Kato, K Horie, T Hagiwara, E Maeda… - Experimental …, 1996 - europepmc.org
The recently cloned factor thrombopoietin (TPO) has been shown to exhibit megakaryocyte
colony-stimulating activity in vitro. In this investigation, to further evaluate the action of TPO …

Proliferative and differentiative potential of thrombopoietin-responsive precursors: expression of megakaryocytic and erythroid lineages.

T Higuchi, K Koike, N Sawai, T Koike - Experimental hematology, 1997 - europepmc.org
We investigated changes in proliferative potential and surface markers during human
megakaryocytic differentiation, using megakaryocytic cells grown by thrombopoietin (TPO) …

[HTML][HTML] Erythropoietin-independent erythroid colony formation by bone marrow progenitors exposed to interleukin-11 and interleukin-8

I Corre-Buscail, D Pineau, M Boissinot… - Experimental …, 2005 - Elsevier
OBJECTIVE: Endogenous erythroid colonies (EECs), formed in vitro without erythropoietin
(EPo) or other exogenous cytokines, are characteristic of Polycythemia vera (PV). Our aim …

Expression of transcription factors during megakaryocytic differentiation of CD34+ cells from human cord blood induced by thrombopoietin

K Terui, Y Takahashi, J Kitazawa, T Toki… - The Tohoku journal of …, 2000 - jstage.jst.go.jp
抄録 Although normal megakaryocytic development has been shown to require the
presence of functional GATA-1 and NF-E2 transcription factors in vivo, the roles of other …

Megakaryocytes derived from CD34‐positive cord blood cells produce interleukin‐8

T Higuchi, K Koike, N Sawai… - British journal of …, 1997 - Wiley Online Library
In a serum‐free liquid culture, thrombopoietin (TPO) selectively stimulated the growth of
megakaryocytic cells from CD34‐positive cord blood cells. Using these cultured cells, we …

A novel CD10-positive erythroid cell line, RM10, established from a patient with chronic myelogenous leukemia.

J Hirata, H Sato, H Takahira, S Shiokawa, T Endo… - Leukemia, 1990 - europepmc.org
A novel erythroid cell line, RM10, was established from a long-term bone marrow culture of a
patient with chronic myelogenous leukemia (CML). RM10 cells were positive for periodic …