Clear cell renal cell carcinoma (ccRCC) is one of the most common renal malignancies
worldwide. SLC22A8 plays a key role in renal excretion of organic anions. However, its role …

Melanoma is the most lethal form of skin cancer; it originates in melanocytes, a group of
neural crest‐derived cells that produce melanin. While patients suffering from melanoma …

Purpose. Skin cutaneous melanoma (SKCM) is one of the most malignant and aggressive
cancers with poor prognosis due to its rapid progression towards metastasis. Thus, finding …

Cancer cells down‐regulate different genes to give them a selective advantage in
invasiveness and/or metastasis. The SLC 25A26 gene encodes the mitochondrial carrier …

Background Our previous study showed that SLC22A18 downregulation and promoter
methylation were associated with the development and progression of glioma and the …

In recent years it has become evident that in addition to genetic mutations also epigenetic
alterations are causally related to the development and progression of cancer. The …

BACKGROUND: Aberrant DNA hypermethylation has been implicated as a component of an
epigenetic mechanism that silences genes in cancers. METHODS: We performed a genome …

Objective. Skin cutaneous melanoma (SKCM) is a highly lethal malignancy that poses a
significant threat to human health. Recent research has shown that competing endogenous …

Aberrant DNA methylation is a well-known feature of tumours and has been associated with
metastatic melanoma. However, since melanoma cells are highly heterogeneous, it has …

Molecular studies empowered novel therapeutic strategies against melanoma in recent
years, however, therapy resistance lowers the efficacy of targeted therapies and …