Establishment of SLC7A11‐knockout mouse and its preliminary investigation in melanoma

Y Chen, T Lu, Y Liu, Y Liu, S Bai, Q Chen… - In Vitro Cellular & …, 2023 - Springer
Solute carrier family 7 member 11 (SLC7A11)/xCT is an amino acid transporter that
mediates the cystine uptake and glutamate export, participates in several malignant tumors' …

S100P contributes to promoter demethylation and transcriptional activation of SLC2A5 to promote metastasis in colorectal cancer

M Lin, Y Fang, Z Li, Y Li, X Feng, Y Zhan, Y Xie… - British Journal of …, 2021 - nature.com
Background SLC2A5 is a high-affinity fructose transporter, which is frequently upregulated in
multiple human malignant tumours. However, the function and molecular mechanism of …

Genetics and epigenetics of melanoma (Review) Retraction in/10.3892/ol. 2020.12045

XY Zhang, PY Zhang - Oncology Letters, 2016 - spandidos-publications.com
Cancer affects multiple organs in the body Malignant melanoma involves the invasion of
skin and occasionally mucosal membrane or eye choroidal tissues. The incidence of …

[引用][C] LB1638 Methylation of PSMB9 is involved in determining prognosis and checkpoint therapies in skin cutaneous melanoma via interferon-gamma pathway

X Hu, Z Hu, Q Cheng, H Feng - Journal of Investigative Dermatology, 2023 - Elsevier

Methylation of nonessential genes in cutaneous melanoma–Rule Out hypothesis

IP Gorlov, K Conway, SN Edmiston… - Melanoma …, 2023 - journals.lww.com
Differential methylation plays an important role in melanoma development and is associated
with survival, progression and response to treatment. However, the mechanisms by which …

Genome-wide DNA methylation and RNA expression differences correlate with invasiveness in melanoma cell lines

J Motwani, EJ Rodger, PA Stockwell, BC Baguley… - …, 2021 - Taylor & Francis
Aims & objectives: The aim of this study was to investigate the role of DNA methylation in
invasiveness in melanoma cells. Materials & methods: The authors carried out genome-wide …

[HTML][HTML] DNMT3b-mediated SPAG6 promoter hypermethylation affects lung squamous cell carcinoma development through the JAK/STAT pathway

Q Wu, Y Yan, S Shi, Q Qi, J Han - American Journal of …, 2022 - ncbi.nlm.nih.gov
Background: DNA methylation controls the transcription of genes and is involved in the
development of lung cancer. Our preliminary bioinformatics prediction revealed that sperm …

[HTML][HTML] Decreased methylation of ZNF671 suppresses tumor progression by promoting MAPK6 transcription in laryngeal carcinoma

W Zhang, T Liu, X Li, T Li, X Ma, D Zhao… - International Journal of …, 2023 - ncbi.nlm.nih.gov
Background: Laryngeal squamous cell carcinoma (LSCC) is a malignant tumor of the head
and neck, the exact mechanism of which has not been explored. Methods: By analyzing the …

Prognostic value of the ferroptosis-related gene SLC2A3 in gastric cancer and related immune mechanisms

L Lin, R Que, J Wang, Y Zhu, X Liu, R Xu - Frontiers in genetics, 2022 - frontiersin.org
SLC2A3 is a ferroptosis marker engaged in transmembrane glucose transport. However, the
effect of SLC2A3 on the prognosis of patients with cancer remains unclear. This study aimed …

[HTML][HTML] Multi-omics analysis for ferroptosis-related genes as prognostic factors in cutaneous melanoma

WU Meng, LI Ke, L Yangying, LI Lan… - Journal of Central …, 2024 - ncbi.nlm.nih.gov
Objective Melanoma is highly malignant and heterogeneous. It is essential to develop a
specific prognostic model for improving the patients' survival and treatment strategies …