Significance: Cancer is related to redox biology from many points of view, such as initiation
and promotion, metabolism and growth, invasion and metastasis, vascularization, or through …

The pursuit of effective anticancer therapies has led to a burgeoning interest in the realm of
redox modulation. This review provides a comprehensive exploration of the intricate …

Redox homeostasis is a lifelong pursuit of cancer cells. Depending on the context, reactive
oxygen species (ROS) exert paradoxical effects on cancers; an appropriate concentration …

The cellular REDOX regulatory systems play a central role in maintaining REDOX
homeostasis that is crucial for cell integrity, survival, and proliferation. To date, a substantial …

Oxidative stress acts as a double‐edged sword by being both a promoter and a suppressor
of cancer. Moderate oxidative stress is beneficial for cancer cell proliferative and …

Cancer remains the second leading cause of death worldwide. Research is currently
focused on finding novel anticancer therapies and elucidating their mechanisms of action …

Redox regulation has been proposed to control various aspects of carcinogenesis, cancer
cell growth, metabolism, migration, invasion, metastasis and cancer vascularization. As …

Significance: There are a number of redox-active anticancer agents currently in
development based on the premise that altered redox homeostasis is necessary for cancer …

Redox dysregulation originating from metabolic alterations and dependence on mitogenic
and survival signaling through reactive oxygen species represents a specific vulnerability of …

Reactive oxygen species (ROS) were once considered only as a toxic by-product of aerobic
metabolism. Many studies done in the past several decades, however, revealed that ROS …