BACKGROUND Gap junctional communication (GJC) has been implicated in the control of
cell proliferation. Numerous cancer cells show a decrease or loss of GJC compared to their …

Purpose: Gap junctions composed of connexin proteins have an essential role in
intercellular communication and differentiation. Dysregulation of connexin expression is …

Gap junction-mediated communication is required for normal cellular growth and
differentiation. As cancer is thought to be a manifestation of the breakdown of cell-cell …

Gap‐junction‐mediated intercellular communication (GJIC) is required for completion of
embryonic development, tissue homeostasis, and regulation of cell proliferation and death …

Impaired expression of connexins, the gap junction subunits that facilitate direct cell-cell
communication, have been implicated in prostate cancer growth. To elucidate the crucial …

Gap‐junctional communication and expression of gap junction‐forming proteins were
investigated in normal human prostate epithelial cells and in several malignant prostate cell …

BACKGROUND Connexins have their traditional function as part of gap junction (GJ)
structures, but have recently been shown to have GJ‐independent roles. Although GJs and …

Gap junctions, composed of connexins, provide a pathway of direct intercellular
communication for the diffusion of small molecules between cells. Evidence suggests that …

Connexins (Cxs) are a family of transmembrane proteins that build cell-to-cell channels in
gap junctions. Gap junctions composed of Cxs have an essential role in intercellular …

The cell‐to‐cell channels in gap junctions, formed of proteins called connexins (Cxs),
provide a direct intercellular pathway for the passage of small signaling molecules (≤ 1 kD) …