DNA methylation is an integral part of the mechanism of a remodeling and modification of
the chromatin structure. The global complex net of chromatin modification and remodeling …

DNA methylation is the epigenetic modification, which introduces 5mC as fifth base onto
DNA. As for the distribution of 5mCs, it is well known that they distribute themselves in a non …

DNA methylation is one of the epigenetic modifications of the genome, the essence of which
is the attachment of a methyl group to nitrogenous bases. In the eukaryote genome, cytosine …

Cytosine methylation is a characteristic property of prokaryotic and eukaryotic genomes. In
the latter, it is indispensable for a healthy development of the organism and uncontrolled …

DNA methylation at position C5 of the pyrimidine ring of cytosine in mammalian genomes
has received a great deal of research interest due to its importance in many biological …

Methylation of cytosines is a pervasive feature of eukaryotic genomes and an important
epigenetic layer that is fundamental for cellular differentiation processes and control of …

The fundamental biochemical processes of 5-methylcytosine (5-mC) synthesis,
maintenance, conversion and removal determine the time and spatial pattern of DNA …

Modern approaches for studies on genome functioning include investigation of its epigenetic
regulation. Methylation of cytosines in CpG dinucleotides is an inherited epigenetic …

Abstract DNA (cytosine-5-carbon) methylation is one of the hallmarks of mammalian
chromatin modifications. Distinct methylation pattern can generate synergistic or …

The chemical modification of DNA bases plays a key role in epigenetic gene regulation.
While much attention has been focused on the classical epigenetic mark, 5-methylcytosine …