Regulation of gene expression is a complex process. It includes a great number of steps
from control of mRNA synthesis to posttranslational modification of proteins. Epigenetic …

Publisher Summary The chapter discusses on the DNA methylation and its possible
biological roles. The pattern of DNA methylation is species-specific. In the DNA of some …

Epigenetics refers to a variety of processes that have heritable effects on gene expression
programs without changes in DNA sequence. Key players in epigenetic control are chemical …

Prototypical abnormalities of genome-wide DNA methylation constitute the most widely
investigated epigenetic mechanism in human cancers. Errors in the cellular machinery to …

In the past decade it has become increasingly clear that DNA has the potential to adopt a
variety of unusual secondary structures which deviate from the classical right-handed B …

The genomes of many animals, plants and fungi are tagged by methylation of DNA cytosine.
To understand the biological significance of this epigenetic mark it is essential to know …

DNA methylation is one of the main mechanisms of epigenetic inheritance in eukaryotes. In
this review we looked through the ways of 5-methylcytosin origin, it's distribution in genome …

Significance: Methylation of cytosine in DNA is linked with gene regulation, and this has
profound implications in development, normal biology, and disease conditions in many …

Expression of genetic information is related to the presence of 5-methylcytosine in DNA. The
distribution of 5-methylcytosine varies in different tissues and its frequency is drastically …

The role of DNA methylation and recently discovered hydroxymethylation in the function of
the human epigenome is currently one of the hottest topics in the life sciences. Progress in …