Bioinformatic analysis of next-generation sequencing data to identify dysregulated genes in fibroblasts of idiopathic pulmonary fibrosis

CC Sheu, WA Chang, MJ Tsai… - International …, 2019 - spandidos-publications.com
Idiopathic pulmonary fibrosis (IPF) is a lethal fibrotic lung disease with an increasing global
burden. It is hypothesized that fibroblasts have a number of functions that may affect the …

Molecular pathogenesis involved in human idiopathic pulmonary fibrosis based on an integrated microRNA‑mRNA interaction network

L Wang, W Huang, L Zhang… - Molecular medicine …, 2018 - spandidos-publications.com
Idiopathic pulmonary fibrosis (IPF) is considered to be an ailment of the lungs that cannot be
cured, wherein the lung tissues are characterized by increased thickness and stiffness …

Underlying molecular mechanism and construction of a miRNA-gene network in idiopathic pulmonary fibrosis by bioinformatics

S Zheng, Y Zhang, Y Hou, H Li, J He, H Zhao… - International Journal of …, 2023 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive lung disease, but its
pathogenesis is still unclear. Bioinformatics methods were used to explore the differentially …

[HTML][HTML] Integrated analysis of the molecular mechanisms in idiopathic pulmonary fibrosis

K Zhu, A Xu, W Xia, P Li, R Han, E Wang… - … Journal of Medical …, 2021 - ncbi.nlm.nih.gov
Rationale: Idiopathic pulmonary fibrosis (IPF) is one of the most aggressive forms of
idiopathic interstitial pneumonia. Some miRNAs may be associated with IPF and may affect …

Evaluation of microRNA expression in a sheep model for lung fibrosis

UE Perera, HB Derseh, SNV Dewage, A Stent… - BMC genomics, 2021 - Springer
Background Idiopathic pulmonary fibrosis (IPF) is a chronic progressive fibroproliferative
disorder that has one of the poorest prognoses amongst interstitial lung diseases. Recently …

[HTML][HTML] Identification and validation of potential biomarkers and pathways for idiopathic pulmonary fibrosis by comprehensive bioinformatics analysis

W Qian, X Cai, Q Qian, X Zhang - BioMed research …, 2021 - pmc.ncbi.nlm.nih.gov
Objective Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, irreversible, high-
mortality lung disease, but its pathogenesis is still unclear. Our purpose was to explore …

Screening of biomarkers involved in idiopathic pulmonary fibrosis and regulation of upstream miRNAs

L Gao, P Li, H Tian, M Wu, J Yang, X Xu - The American Journal of the …, 2022 - Elsevier
Background Idiopathic pulmonary fibrosis (IPF) is the most common type of fatal interstitial
lung disease and IPF patients usually have a poor prognosis. Biomarkers that can predict …

Idiopathic pulmonary fibrosis Molecular substrates revealed by competing endogenous RNA Regulatory Networks

MF Kircali, B Turanli - OMICS: A Journal of Integrative Biology, 2023 - liebertpub.com
Idiopathic pulmonary fibrosis (IPF) is a chronic progressive fibrotic disease of the lung with
poor prognosis. Fibrosis results from remodeling of the interstitial tissue. A wide range of …

[HTML][HTML] Weighted gene coexpression network analysis identifies key genes and pathways associated with idiopathic pulmonary fibrosis

Z Wang, J Zhu, F Chen, L Ma - Medical Science Monitor …, 2019 - ncbi.nlm.nih.gov
Background Idiopathic pulmonary fibrosis (IPF) is a life-threatening disease with an
unknown etiology. Gene expression microarray data have provided some insights into the …

Role of microRNAs in signaling pathways associated with the pathogenesis of idiopathic pulmonary fibrosis: a focus on epithelial-mesenchymal transition

AR Cadena-Suárez… - International Journal of …, 2022 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive disease with high mortality
and unclear etiology. Previous evidence supports that the origin of this disease is associated …