[HTML][HTML] Biomarker validation and testing

DF Hayes - Molecular oncology, 2015 - Elsevier
A tumor biomarker is a molecular or process-based change that reflects the status of an
underlying malignancy. A tumor biomarker may be identified and measured by one or more …

New perspectives and strategy research biomarkers for hepatocellular carcinoma

R Saffroy, P Pham, M Reffas, M Takka, A Lemoine… - 2007 - degruyter.com
Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide. Cirrhosis
caused by hepatitis B virus, hepatitis C virus or chronic alcohol intake is associated with …

Hepatocellular carcinoma tumour markers: current role and expectations

N Rich, AG Singal - Best Practice & Research Clinical Gastroenterology, 2014 - Elsevier
Tumour markers could be helpful along the continuum of care for patients with
hepatocellular carcinoma; however, there is insufficient data for routine use of most current …

[HTML][HTML] Diagnosis of hepatocellular carcinoma

ES Bialecki, AM Di Bisceglie - Hpb, 2005 - Elsevier
Hepatocellular carcinoma (HCC) is responsible for a large proportion of cancer deaths
worldwide. HCC is frequently diagnosed after the development of clinical deterioration at …

Elevated alpha-fetoprotein: differential diagnosis-hepatocellular carcinoma and other disorders

RJ Wong, A Ahmed, RG Gish - Clinics in liver disease, 2015 - liver.theclinics.com
Globally, up to approximately 800,000 new cases of hepatocellular carcinoma (HCC) are
diagnosed annually. 1, 2 The incidence of cirrhosis-related HCC is rising in the United …

New serum markers of hepatocellular carcinoma

R Masuzaki, SJ Karp, M Omata - Seminars in oncology, 2012 - Elsevier
Hepatocellular carcinoma (HCC), one of the most common cancers worldwide, usually
develops in a liver already suffering from chronic damages, often cirrhosis. There has been …

Diagnosing and monitoring hepatocellular carcinoma with alpha-fetoprotein: new aspects and applications

EN Debruyne, JR Delanghe - Clinica chimica acta, 2008 - Elsevier
Hepatocellular carcinoma is the 5th most common cancer in the world. Prognosis for this
disease is poor since hepatocellular carcinoma is mostly diagnosed at an advanced stage …

[HTML][HTML] Circulating predictive and diagnostic biomarkers for hepatitis B virus-associated hepatocellular carcinoma

S Van Hees, P Michielsen… - World journal of …, 2016 - ncbi.nlm.nih.gov
Chronic hepatitis B virus (HBV) infected patients have an almost 100-fold increased risk to
develop hepatocellular carcinoma (HCC). HCC is the fifth most common and third most …

Recently introduced biomarkers for screening of hepatocellular carcinoma: a systematic review and meta-analysis

CDM Witjes, SM van Aalten, EW Steyerberg… - Hepatology …, 2013 - Springer
Purpose Early detection of hepatocellular carcinoma (HCC) is essential for improved
prognosis and long-term survival. To date, screening for HCC depends on serological …

Enhanced detection of hepatocellular carcinoma

ME El-Houseini, MS Mohammed… - Cancer …, 2005 - journals.sagepub.com
Background Tumor markers in the early detection of tumors are promising tools that could
improve the control and treatment of tumors. While alpha-fetoprotein (AFP) is a commonly …