Moving cannabinoid production away from the vagaries of plant extraction and into
engineered microbes could provide a consistent, purer, cheaper and environmentally …

During the last decade, the use of medical Cannabis has expanded globally and legislation
is getting more liberal in many countries, facilitating the research on cannabinoids. The …

Modulation of the endocannabinoid system is projected to have therapeutic potential in
almost all human diseases. Accordingly, the high demand for novel cannabinoids stimulates …

Abstract Δ 9-tetrahydrocannabinolic acid (THCA) is a plant derived secondary natural
product from the plant Cannabis sativa l. The discovery of the human endocannabinoid …

Cannabinoids, produced only in Cannabis sativa, are meroterpenoid secondary metabolites
composed of monoterpene and polyketide moieties. Numerous cannabinoids have been …

Microbial fermentation platforms offer a cost-effective and sustainable alternative to plant
cultivation and chemical synthesis for the production of many plant-derived pharmaceuticals …

Cannabis sativa is a source of food, fiber and specialized metabolites such as cannabinoids,
with psychoactive and pharmacological effects. Due to its expanding and increasingly …

Natural products make up a large proportion of medicine available today. Cannabinoids
from the plant Cannabis sativa is one unique class of meroterpenoids that have shown a …

Microbial production of cannabinoids promises to provide a consistent, cheaper, and more
sustainable supply of these important therapeutic molecules. However, scaling production to …

Numerous studies in cannabinoid biotechnology focus extensively on cytosolic biosynthesis
or biotransformation, neglecting to consider non-aqueous solvents. In this study, we show …