Does appropriate empiric antibiotic therapy modify intensive care unit-acquired Enterobacteriaceae bacteraemia mortality and discharge?

KB Pouwels, E Van Kleef, S Vansteelandt… - Journal of Hospital …, 2017 - Elsevier
Background Conflicting results have been found regarding outcomes of intensive care unit
(ICU)-acquired Enterobacteriaceae bacteraemia and the potentially modifying effect of …

Intensive care unit (ICU)-acquired bacteraemia and ICU mortality and discharge: addressing time-varying confounding using appropriate methodology

KB Pouwels, S Vansteelandt, R Batra… - Journal of Hospital …, 2018 - Elsevier
Background Studies often ignore time-varying confounding or may use inappropriate
methodology to adjust for time-varying confounding. Aim To estimate the effect of intensive …

Epidemiology, management, and risk-adjusted mortality of ICU-acquired enterococcal bacteremia

DSY Ong, MJM Bonten, K Safdari… - Clinical Infectious …, 2015 - academic.oup.com
Background. Enterococcal bacteremia has been associated with high case fatality, but it
remains unknown to what extent death is caused by these infections. We therefore …

[HTML][HTML] Mortality in enterococcal bloodstream infections increases with inappropriate antimicrobial therapy

M Suppli, R Aabenhus, ZB Harboe, LP Andersen… - Clinical microbiology …, 2011 - Elsevier
Enterococcus species are common in nosocomial bloodstream infections and their
incidence is rising. Although well recognized in several serious bacterial infections, the …

Gram-negative bacteraemia in non-ICU patients: factors associated with inadequate antibiotic therapy and impact on outcomes

J Marschall, D Agniel, VJ Fraser… - Journal of …, 2008 - academic.oup.com
Background A considerable number of Gram-negative bacteraemias occur outside intensive
care units (ICUs). Inadequate antibiotic therapy in ICUs has been associated with adverse …

[HTML][HTML] The effect of duration of antimicrobial treatment for bacteremia in critically ill patients on in-hospital mortality–Retrospective double center analysis

P Zuercher, A Moser, MC Frey, JL Pagani, N Buetti… - Journal of critical …, 2023 - Elsevier
Purpose Excessive duration of antibiotic treatment is a major factor for inappropriate
antibiotic consumption. Although in some instances shorter antibiotic courses are as efficient …

[HTML][HTML] The association of infectious diseases consultation and 30-day mortality rates among veterans with enterococcal bacteraemia: a propensity score–matched …

J Tholany, H Suzuki, DJ Livorsi, EN Perencevich… - Clinical Microbiology …, 2023 - Elsevier
Objectives Infectious disease consultation (IDC) has been associated with improved
outcomes in several infections, but the benefit of IDC among patients with enterococcal …

Antibiotic use practice and predictors of hospital outcome among patients with systemic bacterial infection: Identifying targets for antibiotic and health care resource …

G Alemkere, A Tenna, E Engidawork - PloS one, 2019 - journals.plos.org
Background Malpractice and excess use of antimicrobials have been associated with
multiple costs, including the development of resistant bacteria, which has become a threat to …

Impact of empirical antimicrobial therapy on the outcome of critically ill patients with Acinetobacter bacteremia

HM Al-Dorzi, AM Asiri, A Shimemri… - Annals of thoracic …, 2015 - journals.lww.com
METHODS: This is a retrospective study of patients admitted to a medical-surgical ICU (2005-
2010) and developed Acinetobacter bacteremia during the stay. Patients were categorized …

Carbapenem-resistant Enterobacteriaceae (CRE) or Delayed Appropriate Therapy (DAT)—Does One Affect Outcomes More Than the Other Among Patients With …

T Lodise, A Berger, A Altincatal, R Wang… - Open Forum …, 2017 - academic.oup.com
Abstract Background While CRE and DAT are both associated with worse outcomes, their
relative impact to the clinical and economic burden among patients with infections due to …