Patients with Alzheimer's disease (AD) exhibit alterations in glucose metabolism and
dysregulation of the stress-responsive hypothalamic-pituitary-adrenal (HPA) …

A number of studies suggest an association between Alzheimer's disease (AD) and
diabetes: AD patients show impaired insulin function, whereas cognitive deficits and …

Introduction Epidemiologic studies have demonstrated an association between diabetes
and dementia. Insulin signaling within the brain, in particular within the hypothalamus …

Increasing epidemiological evidence highlights the association between systemic insulin
resistance and Alzheimer's disease (AD). As insulin resistance can be caused by high-stress …

Elevated cortisol evidence in Alzheimer's disease (AD) patients prompted the hypothesis
that stress and glucocorticoids are involved in the development and/or maintenance of AD …

Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by beta-
amyloid (Aβ) deposition, neurofibrillary tangles and cognitive decline. Clinical data suggests …

Glucose hypometabolism is the earliest symptom observed in the brains of Alzheimer
disease (AD) patients. In a former study, we analyzed the cortical proteome of the APP23 …

Several studies have demonstrated that mouse models of Alzheimer's disease (AD) can
exhibit impaired peripheral glucose tolerance. Further, in the APP/PS1 mouse model, this is …

Background Although increasing evidence has indicated that brain insulin dysfunction is a
risk factor for Alzheimer disease (AD), the underlying mechanisms by which insulin …

Deposition of β-amyloid (Aβ) is a characteristic feature of the pathology of Alzheimer's
disease (AD). Since glucose metabolism and the consequential ATP production are …