Surveillance of antiretroviral drug resistance mutations in untreated young children living in the Central African Republic

C Charpentier, JC Gody, P Tisserand, M Matta, H Péré… - 2011 - journals.sagepub.com
Background A survey of drug resistance-associated mutations (DRMs) was conducted in
2009 among 77 vertically HIV-infected children not treated by antiretroviral drugs, followed …

[PDF][PDF] The burden of HIV associated drug resistance mutations in an early infant diagnosis program: a glance through the paediatric window of Zimbabwe

MT Manhanzva, J Mutsvangwa, IA Beck, LM Frenke… - J Infect Dis …, 2015 - academia.edu
There is paucity of information on the prevalence of human immunodeficiency virus type 1
drug-resistance mutations in infants infected despite prevention of mother to child …

Persistence of HIV drug resistance among South African children given nevirapine to prevent mother-to-child-transmission

R Kanthula, TM Rossouw, UD Feucht, G Van Dyk… - Aids, 2017 - journals.lww.com
Objectives: We set out to examine the prevalence and persistence of mutations conferring
high-level nonnucleoside reverse transcriptase (NNRTI)-resistance in a cohort of HIV …

A case series of acquired drug resistance-associated mutations in human immunodeficiency virus-infected children: an emerging public health concern in rural Africa

A Gamell, L Muri, A Ntamatungiro… - Open forum …, 2016 - academic.oup.com
The acquisition of drug-resistance mutations among African children living with in human
immunodeficiency virus on antiretroviral treatment has been scarcely reported. This …

HIV drug resistance among children initiating first-line antiretroviral treatment in Uganda

C Kityo, KCE Sigaloff, TS Boender… - AIDS research and …, 2016 - liebertpub.com
Background: There are limited data on primary human immunodeficiency virus drug
resistance (HIVDR) in pediatric populations. This study aimed to assess the prevalence of …

HIV-1 drug resistance at antiretroviral treatment initiation in children previously exposed to single-dose nevirapine

GM Hunt, A Coovadia, EJ Abrams, G Sherman… - Aids, 2011 - journals.lww.com
Objective: To describe the prevalence of HIV-1 drug resistance mutations at the time of
treatment initiation in a large cohort of HIV-infected children previously exposed to single …

Added Value of Next Generation over Sanger Sequencing in Kenyan Youth with Extensive HIV-1 Drug Resistance

V Novitsky, W Nyandiko, R Vreeman… - Microbiology …, 2022 - Am Soc Microbiol
ABSTRACT HIV-1 drug resistance testing in children and adolescents in low-resource
settings is both important and challenging. New (more sensitive) drug resistance testing …

Reverse transcriptase genotypes in pediatric patients failing initial antiretroviral therapy in Gaborone, Botswana

M Tolle, L Howard, B Kirk, A Gomila… - Journal of the …, 2012 - journals.sagepub.com
Background Limited data are available on patterns of resistance mutations in pediatric
patients in southern Africa, where HIV-1 subtype C (HIV-1C) predominates. Methods …

HIV-1 drug mutations in children from northern Tanzania

ER Shao, EG Kifaro, IB Chilumba… - Journal of …, 2014 - academic.oup.com
Objectives In resource-limited settings, it is a challenge to get quality clinical specimens due
to poor infrastructure for their collection, transportation, processing and storage. Using dried …

High prevalence of virological failure and HIV drug mutations in a first-line cohort of Malawian children

MHW Huibers, P Moons, M Cornelissen… - Journal of …, 2018 - academic.oup.com
Abstract Background Drug resistance mutations (DRMs) increasingly jeopardize paediatric
HIV programmes in sub-Saharan Africa. As individual monitoring of DRMs and viral loads …