Recurrence-associated genes in papillary thyroid cancer: An analysis of data from The Cancer Genome Atlas

MN Chien, PS Yang, JJ Lee, TY Wang, YC Hsu… - Surgery, 2017 - Elsevier
Background Recurrence of papillary thyroid cancer is not uncommon, but incorporating
clinicopathologic parameters to predict recurrence is suboptimal. The aim of this study was …

Recurrence of papillary thyroid cancer: a systematic appraisal of risk factors

HR Nieto, CEM Thornton, K Brookes… - The Journal of …, 2022 - academic.oup.com
Context Thyroid cancer recurrence is associated with increased mortality and adverse
outcomes. Recurrence risk is currently predicted using clinical tools, often restaging patients …

A novel gene panel for prediction of lymph-node metastasis and recurrence in patients with thyroid cancer

EML Ruiz, T Niu, M Zerfaoui, M Kunnimalaiyaan… - Surgery, 2020 - Elsevier
Background Although well-differentiated papillary thyroid cancer may remain indolent,
lymph node metastases and the recurrence rates are approximately 50% and 20 …

A novel RNA sequencing-based risk score model to predict papillary thyroid carcinoma recurrence

J He, Z Tian, X Yao, B Yao, Y Liu, J Yang - Clinical & Experimental …, 2020 - Springer
The papillary thyroid carcinoma (PTC) usually shows an excellent prognosis. But some
patients suffer recurrence after treatment. Recent progress in RNA sequencing (RNA-Seq) …

Molecular pathways associated with mortality in papillary thyroid cancer

N Nilubol, C Sukchotrat, L Zhang, M He, E Kebebew - Surgery, 2011 - Elsevier
BACKGROUND: A better understanding of the molecular mechanisms involved in papillary
thyroid cancer (PTC)-associated adverse outcome is needed to manage these patients …

Patterns of expression of cell cycle/apoptosis genes along the spectrum of thyroid carcinoma progression

B Saltman, B Singh, CV Hedvat, VB Wreesmann… - Surgery, 2006 - Elsevier
BACKGROUND: Genetic screening studies suggest that genetic changes underlie
progression from well differentiated to anaplastic thyroid cancers. The aim of this study is to …

Molecular pathology of thyroid cancer

CA Cassol, SL Asa - Diagnostic histopathology, 2011 - Elsevier
Thyroid cancer is increasing in incidence. Although often indolent and highly curable
neoplasms, they may recur, metastasize, or become resistant to radio-iodine therapy …

Development of a risk scoring system for patients with papillary thyroid cancer

K Pak, YH Kim, S Suh, TS Goh… - Journal of Cellular …, 2019 - Wiley Online Library
As the importance of personalized therapeutics in aggressive papillary thyroid cancer (PTC)
increases, accurate risk stratification is required. To develop a novel prognostic scoring …

Cell cycle regulators show diagnostic and prognostic utility for differentiated thyroid cancer

A Melck, H Masoudi, OL Griffith, A Rajput… - Annals of Surgical …, 2007 - Springer
Background Differentiated thyroid cancer (DTC) generally has a favorable outcome, but
some patients develop local recurrence and/or distant metastases and ultimately die of their …

Genome-wide appraisal of thyroid cancer progression

VB Wreesmann, RA Ghossein, SG Patel… - The American journal of …, 2002 - Elsevier
Several lines of evidence suggest that follicular cell-derived thyroid cancers represent a
continuum of disease that progresses from the highly curable well-differentiated thyroid …