[HTML][HTML] Characterization of the genomic alterations in poorly differentiated thyroid cancer

Y Lee, SR Moon, JY Seok, JH Lee, S Nam… - Scientific Reports, 2023 - nature.com
Poorly differentiated thyroid carcinoma (PDTC) is a subtype of thyroid cancer that has a high
rate of metastasis or recurrence and a relatively poor prognosis. However, there are few …

Molecular profiling related to poor prognosis in thyroid carcinoma. Combining gene expression data and biological information

C Montero-Conde, JM Martin-Campos, E Lerma… - Oncogene, 2008 - nature.com
Undifferentiated and poorly differentiated thyroid tumors are responsible for more than half
of thyroid cancer patient deaths in spite of their low incidence. Conventional treatments do …

[HTML][HTML] Identification of a five-gene signature and establishment of a prognostic nomogram to predict progression-free interval of papillary thyroid carcinoma

M Wu, H Yuan, X Li, Q Liao, Z Liu - Frontiers in endocrinology, 2019 - frontiersin.org
Background: The incidence of papillary thyroid carcinoma (PTC) is high and increasing
worldwide. Although prognosis is relatively good, it is important to select the minority of …

[HTML][HTML] Identification of key genes of papillary thyroid cancer using integrated bioinformatics analysis

W Liang, F Sun - Journal of endocrinological investigation, 2018 - Springer
Objective To identify novel clinically relevant genes in papillary thyroid carcinoma from
public databases. Methods Four original microarray datasets, GSE3678, GSE3467 …

[HTML][HTML] Identification of potential functional genes in papillary thyroid cancer by co‑expression network analysis

ZX Ao, YC Chen, JM Lu, J Shen… - Oncology …, 2018 - spandidos-publications.com
Interactions between multiple genes are involved in the development of complex diseases.
However, there are few analyses of gene interactions associated with papillary thyroid …

Progress in thyroid cancer genomics: a 40-year journey

JA Fagin, YE Nikiforov - Thyroid, 2023 - liebertpub.com
Background: Very little was known about the molecular pathogenesis of thyroid cancer until
the late 1980s. As part of the Centennial celebration of the American Thyroid Association …

Genome-wide studies in thyroid neoplasia

TJ Giordano - Endocrinology and metabolism clinics of North America, 2008 - Elsevier
There is much interest in the application of genome biology to the field of thyroid neoplasia,
despite the relatively low mortality rate associated with thyroid cancer in general. The …

[HTML][HTML] Transcriptome analysis discloses dysregulated genes in normal appearing tumor-adjacent thyroid tissues from patients with papillary thyroid carcinoma

H He, S Liyanarachchi, W Li, DF Comiskey Jr, P Yan… - Scientific Reports, 2021 - nature.com
Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. The molecular
characteristics of histologically normal appearing tissue adjacent to the tumor (NAT) from …

Cell cycle M-phase genes are highly upregulated in anaplastic thyroid carcinoma

P Weinberger, SR Ponny, H Xu, S Bai, R Smallridge… - Thyroid, 2017 - liebertpub.com
Background: Anaplastic thyroid carcinoma (ATC) accounts for only 3% of thyroid cancers,
yet strikingly, it accounts for almost 40% of thyroid cancer deaths. Currently, no effective …

Genomic hallmarks of thyroid neoplasia

TJ Giordano - Annual Review of Pathology: Mechanisms of …, 2018 - annualreviews.org
The genomic landscape of thyroid cancers that are derived from follicular cells has been
substantially elucidated through the coordinated application of high-throughput genomic …