Tachykinins are widely distributed in the peripheral nervous system of the respiratory,
urinary and gastrointestinal tract, stored in enteric neurons and in peripheral nerve endings …

Tachykinins mediate a variety of physiological processes in the gastrointestinal, pulmonary
and genito-urinary tract mainly through the stimulation of NK1 and NK2 receptors. Preclinical …

More than 10 years of intensive preclinical investigation of selective tachykinin (TK) receptor
antagonists has provided a rationale to the speculation that peripheral neurokinin (NK)-1,-2 …

The peptides of the tachykinin family are widely distributed within the mammalian peripheral
and central nervous systems and play a well-recognized role as excitatory …

In addition to the classical neurotransmitters, acetylcholine and noradrenaline, a wide
number of peptides with neurotransmitter activity have been identified in the past few years …

Offers a state-of-the-art review by international experts on all aspects of tachykinin receptors,
including neuropeptide/peptide and G-protein-linked receptors in general. It covers the …

The tachykinins, exemplified by substance P, are one of the most intensively studied
neuropeptide families. They comprise a series of structurally related peptides that derive …

The tachykinins substance P, neurokinin A and neurokinin B are involved in many
pathophysiological processes. A reverse transcription–polymerase chain reaction (RT-PCR) …

The intrathecal effect of 0.1 to 10 μg of RP-67,580 (3aR, 7aR)-7, 7-diphenyl-2 [1-imino-2 (2-
methoxyphenyl)-ethyl] perhydroisoindol-4-onehydro chloride, CP-96,345 (2S, 3S)-cis-(2 …

The last decade has witnessed major breakthroughs in the study of tachykinin receptors.
The currently described NK-1, NK-2, and NK-3 receptors have been sequenced and cloned …