[HTML][HTML] Probucol suppresses osteoclastogenesis via activating Nrf2 signaling and ameliorates ovariectomy-induced bone loss

J Guo, R Ren, Z Guo, K Sun, J He, J Shao… - International …, 2023 - Elsevier
Osteoporosis is a systemic and endocrine bone disorder distinguished by declined bone
mineral density, compromised bone strength, and destruction of trabecular structure. The …

[HTML][HTML] Effect of Vicenin-2 on ovariectomy-induced osteoporosis in rats

Z Zhang, Q Zhao, T Liu, H Zhao, R Wang, H Li… - Biomedicine & …, 2020 - Elsevier
In worldwide, osteoporosis has become one of the severe public health distress and over
200 million people get affected by tenderness and fissure during their life period. Vicenin-2 …

[HTML][HTML] Oridonin attenuates thioacetamide-induced osteoclastogenesis through MAPK/NF-κB pathway and thioacetamide-inhibited osteoblastogenesis through BMP …

XL Jin, J Xu, F Yang, J Chen, F Luo, B Xu… - Calcified Tissue …, 2023 - Springer
Osteoporosis, an age-related metabolic bone disease, is mainly caused by an imbalance
between osteoblast-mediated bone formation and osteoclast-mediated bone resorption. At …

Puerarin alleviates osteoporosis in rats by targeting the JAK2/STAT3 signaling pathway

X Zhao, J Zhou, Y Liu, J Wang, Y Liu, B Wang… - Biomolecules and …, 2024 - bjbms.org
Osteoporosis (OP) is a common chronic progressive bone disease that increases fracture
risk in postmenopausal women. Research suggests that puerarin (Pue) may be an effective …

[HTML][HTML] Beneficial effects of hyperoside on bone metabolism in ovariectomized mice

Y Chen, F Dai, Y He, Q Chen, Q Xia, G Cheng… - Biomedicine & …, 2018 - Elsevier
Hyperoside, an active flavonoid glycoside isolated from many traditional Chinese medicines,
has received much attention because of its potential role in osteoporosis treatment. In the …

[PDF][PDF] Teriparatide alleviates osteoporosis by promoting osteogenic differentiation of hMSCs via miR-375/RUNX2 axis.

NB Lei, X Liang, P Wang, Q Liu… - European Review for …, 2019 - europeanreview.org
OBJECTIVE: To investigate whether Teriparatide (TP) contributed to the osteogenic
differentiation of human marrow mesenchymal cells (hMSCs) through the regulation of miR …

Daidzein promotes proliferation and differentiation in osteoblastic OCT1 cells via activation of the BMP-2/Smads pathway

B Yu, DZ Tang, SY Li, Y Wu… - Die Pharmazie-An …, 2017 - ingentaconnect.com
Daidzein, the most widely studied soy phytoestrogen, is not only a potential antiosteoporosis
agent owing to its possible osteogenic activity, but also shows anticancer activity. However …

[HTML][HTML] S-Equol enhances osteoblastic bone formation and prevents bone loss through OPG/RANKL via the PI3K/Akt pathway in streptozotocin-induced diabetic rats

Z Xu, J Xu, S Li, H Cui, G Zhang, X Ni, J Wang - Frontiers in Nutrition, 2022 - frontiersin.org
Background This study aimed to explore whether S-Equol delays diabetes-induced
osteoporosis and the molecular mechanisms underlying its therapeutic effects. Materials …

Diosmin, a citrus fruit-derived phlebotonic bioflavonoid protects rats from chronic kidney disease-induced loss of bone mass and strength without deteriorating the …

S Sharma, K Porwal, C Kulkarni, S Pal, P Sihota… - Food & Function, 2022 - pubs.rsc.org
Kidney Disease Improving Global Outcomes (KDIGO) 2017 Clinical Practice Guideline has
recommended treatment decisions for patients with chronic kidney disease (CKD) with …

Swertiamarin, a natural steroid, prevent bone erosion by modulating RANKL/RANK/OPG signaling

MI Hairul-Islam, S Saravanan… - International …, 2017 - Elsevier
Bone erosion is a central feature of rheumatoid arthritis (RA) that is characterized by the
infiltration of the synovial lining by osteoclasts and lymphocytes. In the present study …