Penetration of the Human Pulmonary Epithelium by Aspergillus fumigatus Hyphae

J Fernandes, F Hamidi, R Leborgne… - The Journal of …, 2018 - academic.oup.com
Background The airway epithelium is the first barrier interacting with Aspergillus fumigatus
conidia after their inhalation, suggesting that this structure functions as point of entry of this …

Binding and Germination of Aspergillus fumigatus Conidia on Cultured A549 Pneumocytes

DJ DeHart, DE Agwu, NC Julian… - Journal of Infectious …, 1997 - academic.oup.com
Invasive pulmonary aspergillosis is acquired through inhalation of conidia. Little is known
about early interactions between Aspergillus fumigatus conidia and alveolar epithelial cells …

Phagocytosis of Aspergillus fumigatus conidia by primary nasal epithelial cells in vitro

F Botterel, K Gross, O Ibrahim-Granet, K Khoufache… - BMC microbiology, 2008 - Springer
Background Invasive aspergillosis, which is mainly caused by the fungus Aspergillus
fumigatus, is an increasing problem in immunocompromised patients. Infection occurs by …

An extracellular matrix glues together the aerial‐grown hyphae of Aspergillus fumigatus

A Beauvais, C Schmidt, S Guadagnini… - Cellular …, 2007 - Wiley Online Library
Pulmonary infections due to Aspergillus fumigatus result from the development of a colony of
tightly associated hyphae in contact with the air, either in the alveoli (invasive aspergillosis) …

Bacterial Interactions with Aspergillus fumigatus in the Immunocompromised Lung

A Margalit, JC Carolan, K Kavanagh - Microorganisms, 2021 - mdpi.com
The immunocompromised airways are susceptible to infections caused by a range of
pathogens which increases the opportunity for polymicrobial interactions to occur …

Binding of Aspergillus fumigatus spores to lung epithelial cells and basement membrane proteins: relevance to the asthmatic lung.

IM Bromley, K Donaldson - Thorax, 1996 - thorax.bmj.com
BACKGROUND: Aspergillus fumigatus is an opportunistic pathogen to which asthmatic
subjects are particularly susceptible. The ability of spores of A fumigatus to bind to …

Interactions of Aspergillus fumigatus Conidia with Airway Epithelial Cells: A Critical Review

CA Croft, L Culibrk, MM Moore, SJ Tebbutt - Frontiers in microbiology, 2016 - frontiersin.org
Aspergillus fumigatus is an environmental filamentous fungus that also acts as an
opportunistic pathogen able to cause a variety of symptoms, from an allergic response to a …

Interaction of Aspergillus with human respiratory mucosa: a study with organ culture model

R Amitani, R Kawanami - Medical mycology, 2009 - Taylor & Francis
The interaction of Aspergillus fumigatus with human bronchial mucosa in an organ culture
model, with an air-mucosal interface, was studied. A. fumigatus conidia were inoculated onto …

Pathophysiological aspects of Aspergillus colonization in disease

S Gago, DW Denning, P Bowyer - Medical mycology, 2019 - academic.oup.com
Aspergillus colonization of the lower respiratory airways is common in normal people, and of
little clinical significance. However, in some patients, colonization is associated with severe …

Hide, Keep Quiet, and Keep Low: Properties That Make Aspergillus fumigatus a Successful Lung Pathogen

N Escobar, SR Ordonez, HAB Wösten… - Frontiers in …, 2016 - frontiersin.org
Representatives of the genus Aspergillus are opportunistic fungal pathogens. Their conidia
can reach the alveoli by inhalation and can give rise to infections in immunocompromised …