Predicting the extent of heterogeneity in meta-analysis, using empirical data from the Cochrane Database of Systematic Reviews

RM Turner, J Davey, MJ Clarke… - International journal …, 2012 - academic.oup.com
Background Many meta-analyses contain only a small number of studies, which makes it
difficult to estimate the extent of between-study heterogeneity. Bayesian meta-analysis …

Heterogeneity and statistical significance in meta‐analysis: an empirical study of 125 meta‐analyses

EA Engels, CH Schmid, N Terrin, I Olkin… - Statistics in …, 2000 - Wiley Online Library
For meta‐analysis, substantial uncertainty remains about the most appropriate statistical
methods for combining the results of separate trials. An important issue for meta‐analysis is …

Key concepts in clinical epidemiology: detecting and dealing with heterogeneity in meta-analyses

CP Cordero, AL Dans - Journal of clinical epidemiology, 2021 - Elsevier
In a meta-analysis, a question always arises. Is it worthwhile to combine estimates from
studies of different populations using various formulations of an intervention, evaluating …

Predictive distributions for between‐study heterogeneity and simple methods for their application in Bayesian meta‐analysis

RM Turner, D Jackson, Y Wei… - Statistics in …, 2015 - Wiley Online Library
Numerous meta‐analyses in healthcare research combine results from only a small number
of studies, for which the variance representing between‐study heterogeneity is estimated …

Limitations of meta-analyses of studies with high heterogeneity

PB Imrey - JAMA network open, 2020 - jamanetwork.com
Sabitova et al1 have performed an important service in compiling and summarizing 2
decades of studies on job burnout and satisfaction among physicians and dentists in middle …

Methods for exploring heterogeneity in meta-analysis

F Song, TA Sheldon, AJ Sutton… - Evaluation & the …, 2001 - journals.sagepub.com
In meta-analysis, when the difference in results between studies is greater than would be
expected by chance, one needs to investigate whether the observed variation in results …

Sensitivity of between-study heterogeneity in meta-analysis: proposed metrics and empirical evaluation

NA Patsopoulos, E Evangelou… - International journal of …, 2008 - academic.oup.com
Background Several approaches are available for evaluating heterogeneity in meta-
analysis. Sensitivity analyses are often used, but these are often implemented in various non …

Understanding heterogeneity in meta‐analysis: the role of meta‐regression

WL Baker, C Michael White… - … journal of clinical …, 2009 - Wiley Online Library
Background: Meta‐regression has grown in popularity in recent years, paralleling the
increasing numbers of systematic reviews and meta‐analysis published in the biomedical …

Commentary: Heterogeneity in meta-analysis should be expected and appropriately quantified

JPT Higgins - International journal of epidemiology, 2008 - academic.oup.com
It is generally accepted that meta-analyses should assess heterogeneity, which may be
defined as the presence of variation in true effect sizes underlying the different studies. This …

Steps in undertaking meta-analysis and addressing heterogeneity in meta-analysis

AP Gandhi, MA Shamim, BK Padhi - The Evidence, 2023 - the.evidencejournals.com
Evidence-based research is used to generate, summarise, and understand the best
available practices to inform decision-making. Systematic reviews (SR) and meta-analysis …