The validity of the different versions of the Hamilton depression scale in separating remission rates of placebo and antidepressants in clinical trials of major depression
PR Kyle, OM Lemming, N Timmerby… - Journal of clinical …, 2016 - journals.lww.com
Our objective was to validate the different versions of the Hamilton Depression Scale (HAM-
D) both psychometrically (scalability) and clinically in discriminating antidepressants from …
D) both psychometrically (scalability) and clinically in discriminating antidepressants from …
[HTML][HTML] Randomized, placebo-controlled trials of antidepressants for acute major depression: thirty-year meta-analytic review
J Undurraga, RJ Baldessarini - Neuropsychopharmacology, 2012 - nature.com
Antidepressant–placebo response-differences (RDs) in controlled trials have been
declining, potentially confounding comparisons among older and newer drugs. For clinically …
declining, potentially confounding comparisons among older and newer drugs. For clinically …
Considering the methodological limitations in the evidence base of antidepressants for depression: a reanalysis of a network meta-analysis
K Munkholm, AS Paludan-Müller, K Boesen - BMJ open, 2019 - bmjopen.bmj.com
Objectives To investigate whether the conclusion of a recent systematic review and network
meta-analysis (Cipriani et al) that antidepressants are more efficacious than placebo for …
meta-analysis (Cipriani et al) that antidepressants are more efficacious than placebo for …
Antidepressants and quality of life in patients with major depressive disorder–Systematic review and meta‐analysis of double‐blind, placebo‐controlled RCTs
T Wiesinger, S Kremer, T Bschor… - Acta Psychiatrica …, 2023 - Wiley Online Library
Abstract Background Quality of Life (QoL) is an important outcome in mental disorders. We
investigated whether antidepressant pharmacotherapy improved QoL vs. placebo among …
investigated whether antidepressant pharmacotherapy improved QoL vs. placebo among …
How could depression guidelines be made more relevant and applicable to primary care?: A quantitative and qualitative review of national guidelines
K Hegarty, J Gunn, G Blashki, F Griffiths… - British Journal of …, 2009 - bjgp.org
Background Many guidelines have been developed in the area of depression but there has
been no systematic assessment of their relevance to general practice. Aim To assess …
been no systematic assessment of their relevance to general practice. Aim To assess …
Network meta-analysis of antidepressants
J Warren - The Lancet, 2018 - thelancet.com
In their network meta-analysis of 21 antidepressant drugs for the acute treatment of major
depressive disorder in adults (April 7, p 1357), Andrea Cipriani and colleagues1 show that …
depressive disorder in adults (April 7, p 1357), Andrea Cipriani and colleagues1 show that …
[HTML][HTML] Do side effects of antidepressants impact efficacy estimates based on the Hamilton Depression Rating Scale? A pooled patient-level analysis
F Hieronymus, A Lisinski, E Eriksson… - Translational …, 2021 - nature.com
Abstract The Hamilton Depression Rating Scale (HDRS-17) measures symptoms that may
overlap with common antidepressant side effects (eg, sexual dysfunction), thus making it …
overlap with common antidepressant side effects (eg, sexual dysfunction), thus making it …
Accuracy of Patient Health Questionnaire-9 (PHQ-9) for screening to detect major depression: individual participant data meta-analysis
Objective To determine the accuracy of the Patient Health Questionnaire-9 (PHQ-9) for
screening to detect major depression. Design Individual participant data meta-analysis. Data …
screening to detect major depression. Design Individual participant data meta-analysis. Data …
Response to acute monotherapy for major depressive disorder in randomized, placebo controlled trials submitted to the US Food and Drug Administration: individual …
Objectives To characterize individual participant level response distributions to acute
monotherapy for major depressive disorder in randomized, placebo controlled trials …
monotherapy for major depressive disorder in randomized, placebo controlled trials …
The effects of psychotherapies for major depression in adults on remission, recovery and improvement: a meta-analysis
Background Standardised effect sizes have been criticized because they are difficult to
interpret and offer little clinical information. This meta-analyses examine the extent of actual …
interpret and offer little clinical information. This meta-analyses examine the extent of actual …