Background Sperm ion channel proteins (CatSpers) are essential for sperm hyperactivated
motility, and then penetration through the zona pellucida. The CatSper class of proteins …

CatSper is a unique sperm cation channel-like protein family exclusively expressed in the
testis and plays important roles in sperm functions. The temporal expression profiles of …

Cation channels of sperm (CatSper) are sperm-specific calcium channels with identified
roles in the regulation of sperm function in humans, mice, and horses. We sought to employ …

The Catsper1 gene, whose expression is restricted to male germ cells, has great importance
in reproductive biology because of its function in sperm motility and fertilization. We …

Channel activities, particularly those of calcium channels, have vital roles in the process of
sperm maturation, motility and sperm-egg interaction. A group of the recently discovered ion …

Background CatSper1-4 are a unique family of sperm cation channels, which are exclusively
expressed in the testis and play an important role in sperm motility and male fertility. Despite …

CATSPER1 and CATSPER2 are two cation channel-like proteins exclusively expressed in
the testis and essential for normal sperm motility and male fertility. Using in silico subtraction …

Sperm-specific nonselective cation (CatSper) channels belong to the CatSper family of
genes and are expressed only in sperm and testis (Qi et al., 2007). This family of genes …

CATSPER1 gene encodes a pore-forming and pH-sensing subunit of the CatSper Ca2+-
permeable channel, a protein in the flagellum essential for sperm hyperactivation. Previous …

The CatSper channel is known as one of the most important Ca²⁺ channels on the cell
membrane of mammalian sperm and plays a key role in the motility, hyperactivation and …