High throughput and quantitative measurement of microbial metabolome by gas chromatography/mass spectrometry using automated alkyl chloroformate …
The ability to identify and quantify small molecule metabolites derived from gut microbial–
mammalian cometabolism is essential for the understanding of the distinct metabolic …
mammalian cometabolism is essential for the understanding of the distinct metabolic …
Microbial metabolomics with gas chromatography/mass spectrometry
MM Koek, B Muilwijk, MJ van der Werf… - Analytical …, 2006 - ACS Publications
An analytical method was set up suitable for the analysis of microbial metabolomes,
consisting of an oximation and silylation derivatization reaction and subsequent analysis by …
consisting of an oximation and silylation derivatization reaction and subsequent analysis by …
Analytical platform for metabolome analysis of microbial cells using methyl chloroformate derivatization followed by gas chromatography–mass spectrometry
KF Smart, RBM Aggio, JR Van Houtte… - Nature protocols, 2010 - nature.com
This protocol describes an analytical platform for the analysis of intra-and extracellular
metabolites of microbial cells (yeast, filamentous fungi and bacteria) using gas …
metabolites of microbial cells (yeast, filamentous fungi and bacteria) using gas …
Chemoselective and highly sensitive quantification of gut microbiome and human metabolites
The microbiome has a fundamental impact on the human host's physiology through the
production of highly reactive compounds that can lead to disease development. One class of …
production of highly reactive compounds that can lead to disease development. One class of …
Mass spectrometry-based metabolomics in microbiome investigations
A Bauermeister, H Mannochio-Russo… - Nature Reviews …, 2022 - nature.com
Microbiotas are a malleable part of ecosystems, including the human ecosystem.
Microorganisms affect not only the chemistry of their specific niche, such as the human gut …
Microorganisms affect not only the chemistry of their specific niche, such as the human gut …
Coupling targeted and untargeted mass spectrometry for metabolome-microbiome-wide association studies of human fecal samples
Increasing appreciation of the gut microbiome's role in health motivates understanding the
molecular composition of human feces. To analyze such complex samples, we developed a …
molecular composition of human feces. To analyze such complex samples, we developed a …
[HTML][HTML] New enzymatic and mass spectrometric methodology for the selective investigation of gut microbiota-derived metabolites
C Ballet, MSP Correia, LP Conway, TL Locher… - Chemical …, 2018 - pubs.rsc.org
Gut microbiota significantly impact human physiology through metabolic interaction.
Selective investigation of the co-metabolism of bacteria and their human host is a …
Selective investigation of the co-metabolism of bacteria and their human host is a …
[HTML][HTML] Unlocking the secrets of the microbiome: exploring the dynamic microbial interplay with humans through metabolomics and their manipulation for synthetic …
Metabolomics is a powerful research discovery tool with the potential to measure hundreds
to low thousands of metabolites. In this review, we discuss the application of GC–MS and LC …
to low thousands of metabolites. In this review, we discuss the application of GC–MS and LC …
Expanding coverage of the metabolome for global metabolite profiling
Mass spectrometry-based metabolomics is the comprehensive study of naturally occurring
small molecules collectively known as the metabolome. Given the vast structural diversity …
small molecules collectively known as the metabolome. Given the vast structural diversity …
Optimization of a sample preparation method for the metabolomic analysis of clinically relevant bacteria
R Marcinowska, J Trygg, H Wolf-Watz, T Mortiz… - Journal of …, 2011 - Elsevier
Metabolomics, or metabolite profiling, is an approach that is increasingly used to study the
metabolism of diverse organisms, elucidate biological processes and/or find characteristic …
metabolism of diverse organisms, elucidate biological processes and/or find characteristic …