[HTML][HTML] Serrated polyps of the large intestine: current understanding of diagnosis, pathogenesis, and clinical management

C Rosty, DG Hewett, IS Brown, BA Leggett… - Journal of …, 2013 - Springer
Approximately 30% of colorectal carcinomas develop via the serrated neoplasia pathway
characterized by widespread DNA methylation and frequent BRAF mutation. Serrated …

Serrated polyposis syndrome: time to rethink endoscopic treatment and surveillance

M Pellisé, F Balaguer - Gastrointestinal Endoscopy, 2019 - giejournal.org
Serrated polyposis syndrome (SPS) has emerged as the most frequent colorectal polyposis
syndrome. This entity is associated with an increased risk of colorectal cancer (CRC) and …

Relationship of colonoscopy-detected serrated polyps with synchronous advanced neoplasia in average-risk individuals

C Álvarez, M Andreu, A Castells, E Quintero… - Gastrointestinal …, 2013 - Elsevier
Background Serrated cancers account for 10% to 20% of all colorectal cancers (CRC) and
more than 30% of interval cancers. The presence of proximal serrated polyps and large (≥ …

Endoscopic discrimination of sessile serrated adenomas from other serrated lesions

S Hasegawa, K Mitsuyama, H Kawano… - Oncology …, 2011 - spandidos-publications.com
Sessile serrated adenoma (SSA) is a proposed precursor of colorectal carcinogenesis. This
study aimed to analyze the potential of endoscopy to discriminate SSA from other serrated …

Prevalence and variable detection of proximal colon serrated polyps during screening colonoscopy

CJ Kahi, DG Hewett, DL Norton, GJ Eckert… - Clinical Gastroenterology …, 2011 - Elsevier
BACKGROUND & AIMS:: Colonoscopy screening might have greater protective effects for
prevention of distal than proximal colorectal cancer. Serrated polyps are frequently located …

Serrated polyposis is an underdiagnosed and unclear syndrome: the surgical pathologist has a role in improving detection

CD Crowder, K Sweet, A Lehman… - The American journal of …, 2012 - journals.lww.com
Serrated polyposis syndrome (SPS) is poorly defined and patients have an increased but
unspecified risk for colorectal carcinoma through the serrated pathway. Despite this …

Colorectal cancer screening for the serrated pathway

JC Anderson, A Srivastava - Gastrointestinal Endoscopy …, 2020 - giendo.theclinics.com
Although hyperplastic polyps (HPs) were once believed to have a benign course with little
clinical significance, they are now recognized as part of a broader group of lesions known as …

How does the serrated polyp pathway alter CRC screening and surveillance?

CJ Kahi - Digestive diseases and sciences, 2015 - Springer
Screening and surveillance for colorectal cancer (CRC) reduces mortality through the
detection of early-stage adenocarcinoma, and more importantly the detection and removal of …

[HTML][HTML] Sessile serrated lesions: Searching for the true prevalence

CJ Kahi, DK Rex - Endoscopy International Open, 2021 - thieme-connect.com
The serrated class of colorectal polyps includes hyperplastic polyps (HP), sessile serrated
lesions (SSL), and traditional serrated adenomas (TSA). Among these, SSL are the most …

[HTML][HTML] A retrospective analysis of colorectal serrated lesions from 2005 to 2014 in a single center: importance of the establishment of diagnostic patterns

PSP Oliveira, RB Carvalho, DO Magro… - … research and practice, 2018 - hindawi.com
Background. Serrated colorectal lesions are increasingly recognized as an important
process in the development of colorectal cancer. Endoscopic and histological diagnosis may …