With the approval of calcitonin gene-related peptide (CGRP) and CGRP receptor
monoclonal antibodies by the Federal Drug Administration, a new era in the treatment of …

Introduction: The neuropeptide calcitonin gene-related peptide (CGRP) is recognized as a
critical player in migraine pathophysiology. Excitement has grown regarding CGRP because …

Migraine is a neurological disorder that manifests as a debilitating headache associated
with altered sensory perception. The neuropeptide calcitonin gene-related peptide (CGRP) …

Calcitonin gene‐related peptide (CGRP) is a ubiquitous neuropeptide found at the very
centers of the migraine process, both centrally and peripherally. It has been under careful …

This article highlights the evidence behind the role of CGRP in migraine and the state of
CGRP-based mechanism treatment development. We present a summary of the evidence …

Migraine is a highly prevalent, complex neurological disorder. The burden of disease and
the direct/indirect annual costs are enormous. Thus far, treatment options have been …

Over the past three decades, calcitonin gene-related peptide (CGRP) has emerged as a key
molecule. Provocation experiments have demonstrated that intravenous CGRP infusion …

Migraine is a highly prevalent headache disease that typically affects patients during their
most productive years. Despite significant progress in understanding the underlying …

Over the last 100 years, the discovery of new analgesics has been a complex and difficult
task. However, remarkable progress in the identification of novel molecular targets relevant …

Importance of the field: Migraine is a highly prevalent disabling condition, and the current
treatment options are not satisfactory. The role of calcitonin gene-related peptide (CGRP) in …