Several lines of evidence pointed to an important role for CGRP in migraine. These included
the anatomic colocalization of CGRP and its receptor in sensory fibers innervating pain …

Calcitonin gene-related peptide (CGRP) is a well-studied neuropeptide of relevance for
migraine pathophysiology. Jugular levels of CGRP are increased during migraine attacks …

Migraine is a common neurological disorder that afflicts up to 15% of the adult population in
most countries, with predominance in females. It is characterized by episodic, often disabling …

Therapeutic agents that block the calcitonin gene–related peptide (CGRP) signaling
pathway are a highly anticipated and promising new drug class for migraine therapy …

Based on preclinical and clinical studies, the neuropeptide calcitonin gene-related peptide
(CGRP) is proposed to play a central role in the underlying pathology of migraine. CGRP …

The neuropeptide calcitonin gene‐related peptide is well established as a key player in the
pathogenesis of migraine. Clinical studies show calcitonin gene‐related peptide levels …

Background Monoclonal antibodies against calcitonin gene-related peptide (CGRP) or its
receptor are efficacious for the prevention of migraine headaches. The downstream …

A growing body of evidence has implicated the calcitonin gene–related peptide (CGRP)
receptors in migraine pathophysiology. With the approval of monoclonal antibodies targeting …

Calcitonin gene-related peptide (CGRP) is a promiscuous peptide, similar to many other
members of the calcitonin family of peptides. The potential of CGRP to act on many different …

Migraine is a common neurological disorder that is associated with an increase in plasma
calcitonin gene-related peptide (CGRP) levels. CGRP, a neuropeptide released from …