Migraine is a highly prevalent, disabling neurological disease that significantly affects
patients' quality of life. There are significant unmet needs in the treatment of migraine, which …

ABSTRACT Introduction Calcitonin Gene-Related Peptide (CGRP) has gradually emerged
as a suitable therapeutic target to treat migraine. Considering the social and economic …

Current evidence does not justify the usage of CGRP levels as a biomarker for diagnosing
migraine or for determining the severity of the disease in individual patients. However …

We have enjoyed creating this book at this timepoint where we are starting to see the
therapeutic benefits of the many years of CGRP research, since its discovery nearly 40 years …

Calcitonin-gene-related peptide (CGRP) plays a key role in migraine pathophysiology and
more specifically in the mechanisms underlying peripheral and central sensitization. Here …

Calcitonin gene-related peptide (CGRP) has long been hypothesized to play a key role in
migraine pathophysiology, and the advent of small-molecule antagonists has clearly …

Migraine is a highly disabling neurological pain disorder in which management is frequently
problematic. Most abortive and preventative treatments employed are classically non …

Background Calcitonin gene–related peptide (CGRP) may have a causative role in
migraine. We therefore hypothesized that a CGRP-receptor antagonist might be effective in …

Migraine is a prevalent, disabling neurological disorder involving the trigeminovascular
system. Previous treatments were either originally intended for other conditions and/or …