Background Insulin-like growth factor (IGF) has unique and well-known functions in female
fertility, according to documents reporting improved yield of oocytes, reinforced quality of the …

The role of the insulin-like growth factor (IGF) system has attracted close attention. The
activity of IGF binding proteins (IGFBPs) within the ovary has not been fully elucidated to …

The role of growth hormone (GH) in human fertility is widely debated with some studies
demonstrating improvements in oocyte yield, enhanced embryo quality, and in some cases …

Objective: To review the available information regarding the roles of insulin‐like growth
factor (IGF)‐IGF binding protein (IGFBP) system in ovarian physiology. Design: Studies that …

Various growth factors have been proposed to play endocrine and I or paracrine role in
mammalian ovarian follicular development. The insulin like growth factor 1 (IGF-1) is one …

The number of growth factors involved in female fertility has been extensively studied, but
reluctance to add essential growth factors in culture media has limited progress in optimizing …

EXPERIMENTAL evidence has shown that insulinlike growth factors (IGFs) exert a variety of
effects at the level of murine, rabbit, porcine, and human ovarian cells, thereby raising the …

The insulin-like growth factors (IGF-I and-II) are ubiquitously expressed factors that regulate
cell growth, differentiation and maintenance of differentiated cell function. All aspects of male …

Insulin-like growth factors (IGF) are polypeptides that regulate growth, differentiation and
survival in a multitude of cells and tissues. The IGF system consists of ligands, receptors …

Insulin and IGFs play an important role in cancer initiation and progression, including
ovarian cancer (OC). Epithelial ovarian cancer (EOC) is the most frequent type of OC in …