Chapter 11: Genome-wide association studies
Genome-wide association studies (GWAS) have evolved over the last ten years into a
powerful tool for investigating the genetic architecture of human disease. In this work, we …
powerful tool for investigating the genetic architecture of human disease. In this work, we …
Bioinformatics challenges for genome-wide association studies
Motivation: The sequencing of the human genome has made it possible to identify an
informative set of> 1 million single nucleotide polymorphisms (SNPs) across the genome …
informative set of> 1 million single nucleotide polymorphisms (SNPs) across the genome …
Genome-wide association studies
A Dehghan - Genetic Epidemiology: Methods and Protocols, 2018 - Springer
Genetic association studies have made a major contribution to our understanding of the
genetics of complex disorders over the last 10 years through genome-wide association …
genetics of complex disorders over the last 10 years through genome-wide association …
Bioinformatics challenges in genome-wide association studies (GWAS)
Genome-wide association studies (GWAS) are a powerful tool for investigators to examine
the human genome to detect genetic risk factors, reveal the genetic architecture of diseases …
the human genome to detect genetic risk factors, reveal the genetic architecture of diseases …
Genome-wide association studies
Genome-wide association studies (GWAS) test hundreds of thousands of genetic variants
across many genomes to find those statistically associated with a specific trait or disease …
across many genomes to find those statistically associated with a specific trait or disease …
[PDF][PDF] A short history of the genome-wide association study: where we were and where we are going
S Ikegawa - Genomics & informatics, 2012 - synapse.koreamed.org
Recent rapid advances in genetic research are ushering us into the genome sequence era,
where an individual's genome information is utilized for clinical practice. The most …
where an individual's genome information is utilized for clinical practice. The most …
Benefits and limitations of genome-wide association studies
Genome-wide association studies (GWAS) involve testing genetic variants across the
genomes of many individuals to identify genotype–phenotype associations. GWAS have …
genomes of many individuals to identify genotype–phenotype associations. GWAS have …
10 years of GWAS discovery: biology, function, and translation
Application of the experimental design of genome-wide association studies (GWASs) is now
10 years old (young), and here we review the remarkable range of discoveries it has …
10 years old (young), and here we review the remarkable range of discoveries it has …
Pathway-based approaches for analysis of genomewide association studies
Published genomewide association (GWA) studies typically analyze and report single-
nucleotide polymorphisms (SNPs) and their neighboring genes with the strongest evidence …
nucleotide polymorphisms (SNPs) and their neighboring genes with the strongest evidence …
[图书][B] Genome-wide association studies and genomic prediction
C Gondro, J Van der Werf, B Hayes - 2013 - Springer
Genome-wide association studies (GWAS) have rapidly spread across the globe over the
last few years becoming the de facto approach to identify candidate regions associated with …
last few years becoming the de facto approach to identify candidate regions associated with …