Cardiac arrhythmias significantly contribute to mortality in Duchenne muscular dystrophy
(DMD), a degenerative muscle disease triggered by mutations in the gene encoding for the …

Gene therapy holds great promise for curing Duchenne muscular dystrophy (DMD), the most
common fatal inherited childhood muscle disease. Success of DMD gene therapy depends …

Background Duchenne muscular dystrophy results from mutation of the dystrophin gene,
causing skeletal and cardiac muscle loss of function. The mdx mouse model of Duchenne …

Psychosocial stressors can cause physical inactivity, cardiac damage, and hypotension‐
induced death in the mdx mouse model of Duchenne muscular dystrophy (DMD). Because …

Almost every boy that has Duchenne Muscular Dystrophy (DMD) will develop cardiac
problems. Whereas, it used to be respiratory problems that was the main cause of death in …

Background Duchenne muscular dystrophy (DMD) is an X‐linked disorder characterized by
progressive muscle weakness due to the absence of functional dystrophin. DMD patients …

Dystrophic cardiomyopathy arises from mutations in the dystrophin gene. Dystrophin forms
part of the dystrophin glycoprotein complex and is postulated to act as a membrane …

Weakness and atrophy are key features of Duchenne muscular dystrophy (DMD).
Dystrophin is one of the many proteins within the dystrophin glycoprotein complex (DGC) …

Heart disease is a major health threat for Duchenne/Becker muscular dystrophy patients and
carriers. Expression of a 6–8 kb mini-dystrophin gene in the heart holds promise to change …

Aged mdx mice represent an important model for studying Duchenne cardiomyopathy.
Herein we compared the cardiac phenotypes of 22‐month‐old male and female mdx mice …