Cancer cachexia: Diagnosis, assessment, and treatment

M Sadeghi, M Keshavarz-Fathi, V Baracos… - Critical reviews in …, 2018 - Elsevier
Cancer cachexia is a multi-factorial syndrome, which negatively affects quality of life,
responsiveness to chemotherapy, and survival in advanced cancer patients. Our …

Update on the treatment of cancer cachexia

K Nishie, T Nishie, S Sato, M Hanaoka - Drug Discovery Today, 2023 - Elsevier
Cancer cachexia is a complex multifaceted syndrome involving functional impairment and
changes in body composition that cannot be reversed by nutritional support. Cancer …

Understanding the mechanisms and treatment options in cancer cachexia

K Fearon, J Arends, V Baracos - Nature reviews Clinical oncology, 2013 - nature.com
Cancer cachexia is a metabolic syndrome that can be present even in the absence of weight
loss ('precachexia'). Cachexia is often compounded by pre-existing muscle loss, and is …

Current therapeutic targets in cancer cachexia: a pathophysiologic approach

KC Kadakia, JM Hamilton-Reeves… - American Society of …, 2023 - ascopubs.org
Significant progress in our understanding of cancer cachexia has occurred in recent years.
Despite these advances, no pharmacologic agent has achieved US Food and Drug …

[HTML][HTML] Cancer cachexia, mechanism and treatment

T Aoyagi, KP Terracina, A Raza… - World journal of …, 2015 - ncbi.nlm.nih.gov
It is estimated that half of all patients with cancer eventually develop a syndrome of
cachexia, with anorexia and a progressive loss of adipose tissue and skeletal muscle mass …

Cachexia: a preventable comorbidity of cancer. A TARGET approach

M Muscaritoli, A Molfino, S Lucia, FR Fanelli - Critical reviews in oncology …, 2015 - Elsevier
Although relevant achievements in the treatment of cancer have been obtained, some
barriers still remain in the prevention and treatments of cancer comorbidities, including …

Cancer cachexia: definition, staging, and emerging treatments

J Ni, L Zhang - Cancer management and research, 2020 - Taylor & Francis
Cachexia is a multifactorial disease characterized by weight loss via skeletal muscle and
adipose tissue loss, an imbalance in metabolic regulation, and reduced food intake. It is …

[HTML][HTML] Perspectives of health care professionals on cancer cachexia: results from three global surveys

M Muscaritoli, FR Fanelli, A Molfino - Annals of Oncology, 2016 - Elsevier
Cachexia has a high prevalence in cancer patients, leading to reduced tolerance/response
to treatment and decreased quality of life. Results from three global surveys presented …

Cancer-associated cachexia

VE Baracos, L Martin, M Korc, DC Guttridge… - Nature reviews Disease …, 2018 - nature.com
Cancer-associated cachexia is a disorder characterized by loss of body weight with specific
losses of skeletal muscle and adipose tissue. Cachexia is driven by a variable combination …

Cancer cachexia: beyond weight loss

AR Bruggeman, AH Kamal, TW LeBlanc… - Journal of oncology …, 2016 - ascopubs.org
Cancer cachexia is a multifactorial syndrome characterized by skeletal muscle loss leading
to progressive functional impairment. Despite the ubiquity of cachexia in clinical practice …