In response to injury, hemodynamic changes, or neurohormonal activation, the heart
undergoes a series of structural and functional changes that have been termed cardiac …

Ventricular remodeling, first described in animal models of left ventricular (LV) stress and
injury, occurs progressively in untreated patients after large myocardial infarction and in …

In patients with heart failure, the beneficial effects of drug and device therapies counteract to
some extent ongoing cardiac damage. According to the net balance between these two …

Cardiac remodeling is generally accepted as a determinant of the clinical course of heart
failure (HF). Defined as genome expression resulting in molecular, cellular and interstitial …

Natural history studies in heart failure have shown that increases in left ventricular (LV)
volume and LV mass are directly related to future deterioration in LV performance and a less …

Cardiac remodelling refers to changes in left ventricular structure and function over time,
with a progressive deterioration that may lead to heart failure (HF) development (adverse …

Left ventricular ejection fraction (LVEF) has been the central parameter used for diagnosis
and management in patients with heart failure. A good predictor of adverse outcomes in …

Patients with heart failure show a wide variety of alterations in left ventricular (LV) volume,
mass, and function. The purpose of this study was to define the common patterns of LV …

The prevalence of heart failure is increasing in the western world. Current efforts aim to
identify heart failure at its earliest and preclinical stages in order to begin treatment and …

Heart failure (HF) involves changes in cardiac structure, myocardial composition, myocyte
deformation, and multiple biochemical and molecular alterations that impact heart function …