Periodontitis is a dysbiotic inflammatory disease with an adverse impact on systemic health.
Recent studies have provided insights into the emergence and persistence of dysbiotic oral …

In health, indigenous polymicrobial communities at mucosal surfaces maintain an ecological
balance via both inter‐microbial and host‐microbial interactions that promote their own and …

This commentary provides background, historical context, and a critical assessment of the
concept that microbial dysbiosis drives the pathogenesis of periodontal diseases. It is long …

An emerging concept is the tight relationship between dysbiosis (microbiota imbalance) and
disease. The increase in knowledge about alterations in microbial communities that reside …

In periodontitis, dysbiotic microbial communities exhibit synergistic interactions for enhanced
protection from host defenses, nutrient acquisition, and persistence in an inflammatory …

Inflammation is a driven force in modulating microbial communities, but little is known about
the interplay between colonizing microorganisms and the immune response in periodontitis …

Periodontal disease is classically characterized by progressive destruction of the soft and
hard tissues of the periodontal complex, mediated by an interplay between dysbiotic …

The nexus between periodontal inflammation and the polymicrobial biofilm in the gingival
sulcus is critical to understanding the pathobiology of periodontitis. Both play a major role in …

Recent studies have uncovered novel mechanisms underlying the breakdown of periodontal
host–microbe homeostasis, which can precipitate dysbiosis and periodontitis in susceptible …

The primary etiological agent for the initiation and progression of periodontal disease is the
dental plaque biofilm which is an organized aggregation of microorganisms residing within a …