crease in HDL, whereas hepatic overexpression of scavenger receptor (SR)-BI with gene
transfer reduces atherosclerosis, despite a major reduction in HDL levels. 47, 48 …

Although high high-density lipoprotein (HDL)-cholesterol levels are associated with
decreased cardiovascular risk in epidemiological studies, recent genetic and …

Low high‐density lipoprotein (HDL)‐cholesterol levels are associated with an increased risk
of coronary artery disease (CAD) and myocardial infarction, which has triggered the …

Previous interest in high-density lipoproteins (HDLs) focused on their possible protective
role in atherosclerotic cardiovascular disease (ASCVD). Evidence from genetic studies and …

High-density lipoproteins (HDLs) are strongly related to risk of atherosclerotic cardiovascular
disease. Low levels of HDL cholesterol are a major cardiovascular risk factor, and …

Observational studies provide overwhelming evidence that a low high-density lipoprotein
(HDL)–cholesterol level increases the risk of coronary events, both in healthy subjects and …

This review aims to provide an overview on the properties of high‐density lipoproteins
(HDLs) and their cardioprotective effects. Emergent HDL therapies will be presented in the …

High-density lipoprotein (HDL) is well established as a negative risk factor for the
development of atherosclerosis. Epidemiologic, pathologic, and experimental studies have …

Population studies from all parts of the world have consistently reported that a low plasma
level of high-density lipoprotein (HDL) cholesterol is a strong predictor of coronary heart …

Despite dramatic improvement in treatments for reducing risk for coronary heart disease
(CHD), it is still the leading cause of mortality in the developed world. In the past decade, a …