Critical environmental factors like physical threats, air pollution, and infections, alongside
social determinants of health (SDH)(Ibáñez et al., 2023) such as social disparities …

With ever-increasing elder populations, age-related cognitive decline, which is
characterized as a gradual decline in cognitive capacity in the aging process, has turned out …

Common brain abnormalities in cortical morphology and functional organization are
observed in psychiatric disorders and aging, reflecting shared genetic influences. This …

Most patients with late-onset neurodegenerative diseases such as Alzheimer's and
Parkinson's have a complex aetiology resulting from numerous genetic risk variants of small …

Aging begins during development and establishes a framework for later events. The process
occurs through the lifespan and is influenced by individual genetics and life events. Such life …

The relationship between genetic variation and gene expression in individual brain cell
types and subtypes has remained elusive. Here, we generated single-nucleus RNA …

With the continuous increase of the elderly population, there is an urgency to understand
and develop relevant treatments for Alzheimer's disease and related dementias (ADRD). In …

Aging is accompanied by a host of social and biological changes that correlate with
behavior, cognitive health and susceptibility to neurodegenerative disease. To understand …

Brain disease represents one of the major social and economic burden worldwide.
Identifying the factors impacting brain homeostasis, as well as the mechanisms involved in …

Networks are present in many aspects of our lives, and networks in neuroscience have
recently gained much attention leading to novel representations of brain connectivity. The …