Gut microbes and their metabolites are actively involved in the development and regulation
of host immunity, which can influence disease susceptibility. Herein, we review the most …

The gut microbiome lies at the intersection between the environment and the host, with the
ability to modify host responses to disease-relevant exposures and stimuli. This is evident in …

To maintain health, the immune system must maintain a delicate balance between
eliminating invading pathogens and avoiding immune disorders such as autoimmunity and …

Neonates face unique challenges in the period following birth. The postnatal immune
system is in the early stages of development and has a range of functional capabilities that …

The gut microbiota have long been recognized to play a key role in human health and
disease. Currently, several lines of evidence from preclinical to clinical research have …

Gut microbiome has been increasingly recognized for its influence on a diverse array of
human diseases including cancer, and may also influence the outcome of cancer therapies …

The immune system must constantly monitor the gastrointestinal tract for the presence of
pathogens while tolerating trillions of commensal microbiota. It is clear that intestinal …

The distal gut harbours∼ 1013 bacteria, representing the most densely populated
ecosystem known. The functional diversity expressed by these communities is enormous …

Keeping a delicate balance in the immune system by eliminating invading pathogens, while
still maintaining self-tolerance to avoid autoimmunity, is critical for the body's health. The gut …

A complex relationship between the microbiota and the host emerges early at birth and
continues throughout life. The microbiota includes the prokaryotes, viruses and eukaryotes …