Quantification of regional myocardial oxygen metabolism in normal pigs using positron emission tomography with injectable 15OO2

T Temma, H Iida, T Hayashi, N Teramoto… - European journal of …, 2010 - Springer
Purpose Although 15 OO 2 gas inhalation can provide a reliable and accurate myocardial
metabolic rate for oxygen by PET, the spillover from gas volume in the lung distorts the …

Noninvasive Quantification of Regional Myocardial Metabolic Rate of Oxygen by 15O2 Inhalation and Positron Emission Tomography: Experimental Validation

Y Yamamoto, R de Silva, CG Rhodes, H Iida… - Circulation, 1996 - Am Heart Assoc
Background The purpose of this study was to validate a novel method for noninvasive
quantification of regional myocardial oxygen consumption (MMRo2, mL· min− 1· 100 g− 1) …

Noninvasive Quantification of Regional Myocardial Metabolic Rate for Oxygen by Use of 15O2 Inhalation and Positron Emission Tomography: Theory, Error Analysis …

H Iida, CG Rhodes, LI Araujo, Y Yamamoto… - Circulation, 1996 - Am Heart Assoc
Background A method has been developed to measure the regional myocardial metabolic
rate of oxygen consumption (rMMRo2) and oxygen extraction fraction (rOEF) quantitatively …

Myocardial oxygen extraction fraction measured using bolus inhalation of 15O-oxygen gas and dynamic PET

M Lubberink, YY Wong… - Journal of Nuclear …, 2011 - Soc Nuclear Med
The aim of this study was to determine the accuracy of oxygen extraction fraction (OEF)
measurements using a dynamic scan protocol after bolus inhalation of 15O2. The method of …

Regional myocardial metabolic rate of oxygen measured by O2-15 inhalation and positron emission tomography in patients with cardiomyopathy

D Agostini, II HIDEHIRO DA, A Takahashi… - Clinical nuclear …, 2001 - journals.lww.com
Background Positron emission tomography (PET) metabolic studies have investigated the
pathways involved in fatty acid, glucose, and oxidative metabolism in cardiomyopathy and …

Measurement of myocardial blood flow with oxygen-15 labelled water: comparison of different administration protocols

F Hermansen, SD Rosen, F Fath-Ordoubadi… - European journal of …, 1998 - Springer
Positron emission tomography (PET) in conjunction with C 15 O 2 or H 2 15 O can be used
to measure myocardial blood flow (MBF) and tissue fraction (TF), ie the fraction of the tissue …

Feasibility study of PET dynamic imaging of [18F] DHMT for quantification of reactive oxygen species in the myocardium of large animals

J Wu, NE Boutagy, Z Cai, S Lin, MQ Zheng… - Journal of Nuclear …, 2022 - Elsevier
Objectives We aimed to develop a dynamic imaging technique for a novel PET superoxide
tracer,[18 F] DHMT, to allow for absolute quantification of myocardial reactive oxygen …

Quantitative measurement of oxygen metabolic rate in the rat brain using microPET imaging of briefly inhaled 15O-labelled oxygen gas

SH Yee, K Lee, PA Jerabek, PT Fox - Nuclear medicine …, 2006 - journals.lww.com
Objective The quantitative measurement of cerebral metabolic rate of oxygen (CMRO 2) for
rats using positron emission tomography (PET) has been technically difficult. The present …

Validity of using a 3-dimensional PET scanner during inhalation of 15O-labeled oxygen for quantitative assessment of regional metabolic rate of oxygen in man

Y Hori, Y Hirano, K Koshino, T Moriguchi… - Physics in Medicine …, 2014 - iopscience.iop.org
Use of 15 O labeled oxygen (15 O 2) and positron emission tomography (PET) allows
quantitative assessment of the regional metabolic rate of oxygen (CMRO 2) in vivo, which is …

Clinical applications of myocardial perfusion assessments made with oxygen-15 water and positron emission tomography

SR Bergmann - Cardiology, 1997 - karger.com
Positron emission tomography is an intrinsically quantitative tool which permits the
quantitative assessment (ie, in ml/g/min) of regional myocardial perfusion. Oxygen-15 …