[HTML][HTML] The regulation of antiviral innate immunity through non-m6A RNA modifications

S Shen, LS Zhang - Frontiers in Immunology, 2023 - frontiersin.org
The post-transcriptional RNA modifications impact the dynamic regulation of gene
expression in diverse biological and physiological processes. Host RNA modifications play …

[HTML][HTML] The emerging role of RNA modifications in the regulation of antiviral innate immunity

J Tong, W Zhang, Y Chen, Q Yuan, NN Qin… - Frontiers in …, 2022 - frontiersin.org
Posttranscriptional modifications have been implicated in regulation of nearly all biological
aspects of cellular RNAs, from stability, translation, splicing, nuclear export to localization …

[HTML][HTML] Regulation of Antiviral Immune Response by N6-Methyladenosine of mRNA

B Zhao, W Wang, Y Zhao, H Qiao, Z Gao… - Frontiers in …, 2021 - frontiersin.org
Host innate and adaptive immune responses play a vital role in clearing infected viruses.
Meanwhile, viruses also evolve a series of mechanisms to weaken the host immune …

Regulation of antiviral innate immunity by chemical modification of viral RNA

N Li, TM Rana - Wiley Interdisciplinary Reviews: RNA, 2022 - Wiley Online Library
More than 100 chemical modifications of RNA, termed the epitranscriptome, have been
described, most of which occur in prokaryotic and eukaryotic ribosomal, transfer, and …

[HTML][HTML] Emerging Perspectives of RNA N6-methyladenosine (m6A) Modification on Immunity and Autoimmune Diseases

L Tang, X Wei, T Li, Y Chen, Z Dai, C Lu… - Frontiers in …, 2021 - frontiersin.org
N 6-methyladenosine (m6A) modification, the addition of a methylation decoration at the
position of N6 of adenosine, is one of the most prevalent modifications among the over 100 …

[HTML][HTML] Global profiling reveals common and distinct N6-methyladenosine (m6A) regulation of innate immune responses during bacterial and viral infections

J Feng, T Zhang, O Sorel, W Meng, X Zhang, Z Lai… - Cell Death & …, 2022 - nature.com
Abstract N 6-methyladenosine (m6A) is a dynamic post-transcriptional RNA modification
influencing all aspects of mRNA biology. While m6A modifications during numerous viral …

The m6A epitranscriptome opens a new charter in immune system logic

Z Ma, X Gao, Y Shuai, X Xing, J Ji - Epigenetics, 2021 - Taylor & Francis
ABSTRACT N6-methyladenosine (m6A), the most prevalent RNA internal modification, is
present in most eukaryotic species and prokaryotes. Studies have highlighted an intricate …

[HTML][HTML] Potential roles of N6-methyladenosine (m6A) in immune cells

C Liu, Z Yang, R Li, Y Wu, M Chi, S Gao, X Sun… - Journal of Translational …, 2021 - Springer
Abstract N6-methyl-adenosine (m6A) is one of the most common internal modifications on
RNA molecules present in mammalian cells. Deregulation of m6A modification has been …

[HTML][HTML] N6-methyladenosine RNA modification suppresses antiviral innate sensing pathways via reshaping double-stranded RNA

W Qiu, Q Zhang, R Zhang, Y Lu, X Wang, H Tian… - Nature …, 2021 - nature.com
Double-stranded RNA (dsRNA) is a virus-encoded signature capable of triggering
intracellular Rig-like receptors (RLR) to activate antiviral signaling, but whether intercellular …

[HTML][HTML] N6-Methyladenosine and Viral Infection

W Dang, Y Xie, P Cao, S Xin, J Wang, S Li… - Frontiers in …, 2019 - frontiersin.org
N6-methyladenosine (m6A), as a dynamic posttranscriptional RNA modification, recently
gave rise to the field of viral epitranscriptomics. The interaction between virus and host is …