The roles of autophagy in cancer
CW Yun, SH Lee - International journal of molecular sciences, 2018 - mdpi.com
Autophagy is an intracellular degradative process that occurs under several stressful
conditions, including organelle damage, the presence of abnormal proteins, and nutrient …
conditions, including organelle damage, the presence of abnormal proteins, and nutrient …
The dual role of autophagy in cancer development and a therapeutic strategy for cancer by targeting autophagy
CW Yun, J Jeon, G Go, JH Lee, SH Lee - International journal of …, 2020 - mdpi.com
Autophagy is a delicate intracellular degradation process that occurs due to diverse stressful
conditions, including the accumulation of damaged proteins and organelles as well as …
conditions, including the accumulation of damaged proteins and organelles as well as …
Autophagy as a molecular target for cancer treatment
Autophagy is an evolutionarily conserved catabolic mechanism, by which eukaryotic cells
recycle or degrades internal constituents through membrane-trafficking pathway. Thus …
recycle or degrades internal constituents through membrane-trafficking pathway. Thus …
[HTML][HTML] Autophagy regulation in cancer development and therapy
Autophagy is a cellular process to degrade long-lived or malfunctioning proteins and
obsolete or damaged organelles. It maintains cellular homeostasis and helps cells survive …
obsolete or damaged organelles. It maintains cellular homeostasis and helps cells survive …
Is targeting autophagy mechanism in cancer a good approach? The possible double-edge sword effect
SM Lim, EA Mohamad Hanif, SF Chin - Cell & bioscience, 2021 - Springer
Autophagy is a conserved cellular process required to maintain homeostasis. The hallmark
of autophagy is the formation of a phagophore that engulfs cytosolic materials for …
of autophagy is the formation of a phagophore that engulfs cytosolic materials for …
Challenges and therapeutic opportunities of autophagy in cancer therapy
VR Silva, SP Neves, LS Santos, RB Dias, DP Bezerra - Cancers, 2020 - mdpi.com
Simple Summary Autophagy is a physiological process characterized by the degradation of
the cell components through lysosomes due to stimuli/stress. In this study, we review the …
the cell components through lysosomes due to stimuli/stress. In this study, we review the …
Understanding the role of autophagy in cancer formation and progression is a real opportunity to treat and cure human cancers
Simple Summary The modulation of autophagy represents a potential therapeutic strategy
for cancer. More than one hundred clinical trials have been conducted or are ongoing to …
for cancer. More than one hundred clinical trials have been conducted or are ongoing to …
Inhibiting autophagy to prevent drug resistance and improve anti-tumor therapy
Cytotoxic drugs remain the first-line option for cancer therapy but the development of drug-
resistance by tumor cells represents a primary obstacle for successful chemotherapy …
resistance by tumor cells represents a primary obstacle for successful chemotherapy …
Targeting cancer cells through autophagy for anticancer therapy
S Turcotte, AJ Giaccia - Current opinion in cell biology, 2010 - Elsevier
Autophagy is a cellular degradation process in which portions of the cell's cytoplasm and
organelles are sequestered in a double-membrane bound vesicle called an …
organelles are sequestered in a double-membrane bound vesicle called an …