The current and future therapies for human osteosarcoma
JD Lamplot, S Denduluri, J Qin, R Li… - Current cancer …, 2013 - ingentaconnect.com
Osteosarcoma (OS) is the most common non-hematologic malignant tumor of bone in adults
and children. As sarcomas are more common in adolescents and young adults than most …
and children. As sarcomas are more common in adolescents and young adults than most …
Current therapeutic strategies and novel approaches in osteosarcoma
K Ando, MF Heymann, V Stresing, K Mori, F Rédini… - Cancers, 2013 - mdpi.com
Osteosarcoma is the most frequent malignant primary bone tumor and a main cause of
cancer-related death in children and adolescents. Although long-term survival in localized …
cancer-related death in children and adolescents. Although long-term survival in localized …
Osteosarcoma treatment: state of the art
HT Ta, CR Dass, PFM Choong, DE Dunstan - Cancer and Metastasis …, 2009 - Springer
Osteosarcoma (OS) is a class of cancer originating from bone, mainly afflicting children or
young adults. It is the second highest cause of cancer-related death in these age groups …
young adults. It is the second highest cause of cancer-related death in these age groups …
Management of osteosarcoma
J Whelan, B Seddon, M Perisoglou - Current Treatment Options in …, 2006 - Springer
Opinion statement Improving cure rates for osteosarcoma continues to be a major challenge.
The clinical management of individual patients is exacting and requires a skilled …
The clinical management of individual patients is exacting and requires a skilled …
Advancing therapy for osteosarcoma
Improving the survival of patients with osteosarcoma has long proved challenging, although
the treatment of this disease is on the precipice of advancement. The increasing feasibility of …
the treatment of this disease is on the precipice of advancement. The increasing feasibility of …
State-of-the-art, approved therapeutics for the pharmacological management of osteosarcoma
C Meazza, SD Asaftei - Expert Opinion on Pharmacotherapy, 2021 - Taylor & Francis
Introduction: Advances in the treatment of osteosarcoma (OS) came in the mid-1970s, when
adding chemotherapy to surgery significantly improved patient survival. OS outcomes have …
adding chemotherapy to surgery significantly improved patient survival. OS outcomes have …
Osteosarcoma
HC Beird, SS Bielack, AM Flanagan, J Gill… - Nature reviews Disease …, 2022 - nature.com
Osteosarcoma is the most common primary malignant tumour of the bone. Osteosarcoma
incidence is bimodal, peaking at 18 and 60 years of age, and is slightly more common in …
incidence is bimodal, peaking at 18 and 60 years of age, and is slightly more common in …
New targets and approaches in osteosarcoma
Osteosarcoma is the most common primary tumor of bone. Approximately 2/3 of patients
who present with localized osteosarcoma can be expected to be cured of their disease with …
who present with localized osteosarcoma can be expected to be cured of their disease with …
Osteosarcoma: accelerating progress makes for a hopeful future
AJ Saraf, JM Fenger, RD Roberts - Frontiers in oncology, 2018 - frontiersin.org
Patients who develop osteosarcoma in 2017 receive treatment that remains essentially
unchanged since the 1970s. Outcomes likewise remain largely unimproved. Large …
unchanged since the 1970s. Outcomes likewise remain largely unimproved. Large …
Molecular pathogenesis and therapeutic strategies of human osteosarcoma
SK Denduluri, Z Wang, Z Yan, J Wang… - Journal of …, 2015 - pmc.ncbi.nlm.nih.gov
Osteosarcoma (OS) is a devastating illness with rapid rates of dissemination and a poor
overall prognosis, despite aggressive standard-of-care surgical techniques and combination …
overall prognosis, despite aggressive standard-of-care surgical techniques and combination …