The latest drugs in development that reduce intraocular pressure in ocular hypertension and glaucoma

V Jayanetti, S Sandhu, JA Lusthaus - Journal of Experimental …, 2020 - Taylor & Francis
Glaucoma causes irreversible vision loss, with elevated intraocular pressure (IOP) being the
only known modifiable risk factor. There are a variety of medical and interventional options …

Current situation and progress of drugs for reducing intraocular pressure

P Liu, F Wang, Y Song, M Wang… - … advances in chronic …, 2022 - journals.sagepub.com
Glaucoma, the most common cause of irreversible blindness worldwide, usually causes
characteristic optic nerve damage. Pathological intraocular pressure (IOP) elevation is a …

New pharmacotherapy for the treatment of glaucoma

EM Schehlein, G Novack, AL Robin - Expert Opinion on …, 2017 - Taylor & Francis
Introduction: Glaucoma is the second leading cause of blindness in the world and current
pharmacotherapies for glaucoma have remained relatively unchanged (with the exception of …

Investigational and experimental drugs for intraocular pressure reduction in ocular hypertension and glaucoma

JA Lusthaus, I Goldberg - Expert Opinion on Investigational Drugs, 2016 - Taylor & Francis
Introduction: Intraocular pressure (IOP) is the most significant modifiable risk factor to
prevent onset or progression of glaucoma. Glaucoma prevalence continues to increase …

The management of glaucoma and intraocular hypertension: current approaches and recent advances

RJ Noecker - Therapeutics and clinical risk management, 2006 - Taylor & Francis
In the last decade, numerous novel ocular hypotensive agents have been introduced for the
control of intraocular pressure (IOP). Clinicians now have more options than ever in the …

Emerging drugs for the treatment of glaucoma: a review of phase II & III trials

TM Kaplan, AJ Sit - Expert Opinion on Emerging Drugs, 2022 - Taylor & Francis
Introduction Glaucoma is a progressive optic neuropathy and the leading cause of
irreversible vision loss. By 2040, the number of individuals with glaucoma is expected to …

Emerging drugs for ocular hypertension

AJ Lee, I Goldberg - Expert opinion on emerging drugs, 2011 - Taylor & Francis
Introduction: Glaucoma is a prevalent ocular disease with characteristic optic disc and visual
field changes. Globally, it is the second most common cause of visual disability, and the …

Controversies in glaucoma: current medical treatment and drug development

C Bucolo, C Bianca Maria Platania… - Current …, 2015 - ingentaconnect.com
Elevated eye pressure is the main risk factor for glaucoma; intraocular pressure rises when
the ratio between aqueous humor formation (inflow) and its outflow is unbalanced. Currently …

Pharmacotherapy of glaucoma

D Schmidl, L Schmetterer, G Garhöfer… - Journal of Ocular …, 2015 - liebertpub.com
Glaucoma is a group of diseases involving the optic nerve and associated structures, which
is characterized by progressive visual field loss and typical changes of the optic nerve head …

Glaucoma drugs in the pipeline

PL Kaufman, ME Mohr, SP Riccomini… - The Asia-Pacific …, 2018 - journals.lww.com
Glaucoma is a chronic disease that can be challenging to treat for both patients and
physicians. Most patients will require more than 1 medication over time to maintain their …