[HTML][HTML] Novel therapies for open-angle glaucoma

SM Wentz, NJ Kim, J Wang, A Amireskandari… - F1000prime …, 2014 - ncbi.nlm.nih.gov
Open-angle glaucoma is a multifactorial optic neuropathy characterized by progressive loss
of retinal ganglion cells and their axons. It is an irreversible disease with no established …

Intraocular pressure–lowering effects of all commonly used glaucoma drugs: a meta-analysis of randomized clinical trials

R van der Valk, CAB Webers, JSAG Schouten… - Ophthalmology, 2005 - Elsevier
OBJECTIVE: To estimate the intraocular pressure (IOP) reduction achieved by the most
frequently prescribed glaucoma drugs and a placebo in a meta-analysis of randomized …

Secondary neuroprotective effects of hypotensive drugs and potential mechanisms of action

GC Shih, DJ Calkins - Expert Review of Ophthalmology, 2012 - Taylor & Francis
Primary open-angle glaucoma, a long-term degenerative ocular neuropathy, remains a
significant cause of vision impairment worldwide. While many risk factors have been …

Advances in glaucoma therapeutics

IH Pang, AF Clark - Expert opinion on emerging drugs, 2002 - Taylor & Francis
Glaucoma is a major cause of irreversible blindness in the world. The prevalence of
glaucomatous loss in vision will continue to grow as our populations age. Ocular …

Short-and long-term safety of glaucoma drugs

JS Schuman - Expert Opinion on Drug Safety, 2002 - Taylor & Francis
Glaucoma, a leading cause of blindness worldwide, is a chronic neurodegenerative
disorder. Patients with glaucoma may require long-term administration of intraocular …

Current and emerging medical therapies for glaucoma

JC Tsai, EM Kanner - Expert opinion on emerging drugs, 2005 - Taylor & Francis
Glaucoma is a multifactorial optic neuropathy in which there is a characteristic acquired loss
of retinal ganglion cells, at levels beyond normal age-related baseline loss, and …

Intraocular pressure-lowering combination therapies with prostaglandin analogues

F Aptel, C Chiquet, JP Romanet - Drugs, 2012 - Springer
Intraocular pressure (IOP) reduction is currently the only therapeutic approach demonstrated
to preserve visual function in patients with glaucoma. The first line of glaucoma treatment …

Glaucoma-next generation therapeutics: impossible to possible

CM Adams, R Stacy, N Rangaswamy, C Bigelow… - Pharmaceutical …, 2019 - Springer
The future of next generation therapeutics for glaucoma is strong. The recent approval of two
novel intraocular pressure (IOP)-lowering drugs with distinct mechanisms of action is the first …

Glaucoma: a brief review

N Schellack, S Bezuidenhout - SA Pharmaceutical Journal, 2015 - journals.co.za
Glaucoma is a complex condition of the eye. It is an ophthalmic neurodegenerative condition
and is characterised by raised intraocular pressure. When left untreated, patients may …

Pharmacological management of primary open-angle glaucoma: second-line options and beyond

CAB Webers, HJM Beckers, RMMA Nuijts… - Drugs & aging, 2008 - Springer
Glaucoma is one of the leading causes of blindness worldwide. Increased intraocular
pressure (IOP) is considered to be the most important risk factor. Major outcome studies from …