Target pressures in glaucoma

T Zeyen - Pathogenesis and Risk factors of Glaucoma, 1999 - Springer
Despite exciting progress in the field of neuroprotection, lowering the intraocular pressure
(IOP) is still the only available option to treat glaucoma patients. Several studies have shown …

Emerging trabecular outflow drugs

CC Kopczynski, DL Epstein - Journal of ocular pharmacology and …, 2014 - liebertpub.com
Glaucoma is a progressive optic neuropathy that is a leading cause of irreversible blindness
worldwide. 1 Elevated intraocular pressure (IOP) is commonly associated with glaucoma …

Canadian journal of ophthalmology lecture: translational research advances in glaucoma neuroprotection

JC Tsai - Canadian Journal of Ophthalmology, 2013 - Elsevier
Given that glaucoma is a disease of the central nervous system, there must be greater
emphasis and focus on developing intraocular pressure–independent therapies. In addition …

New therapeutic targets for intraocular pressure lowering

A Rocha-Sousa, J Rodrigues-Araújo… - International …, 2013 - Wiley Online Library
Primary open‐angle glaucoma (POAG) is a leading cause of irreversible and preventable
blindness and ocular hypertension is the strongest known risk factor. With current classes of …

Pharmacological therapy for glaucoma: a review

PFJ Hoyng, LM van Beek - Drugs, 2000 - Springer
For some time the medical treatment of glaucoma has consisted of topical β-blockers,
adrenergic agents, miotics and oral carbonic anhydrase inhibitors (CAIs). However, the …

Achievements and limits of current medical therapy of glaucoma

P Kalouda, C Keskini, E Anastasopoulos… - Glaucoma surgery, 2017 - karger.com
Prescribing medical therapy for the treatment of glaucoma can be a complex process since
many parameters should be taken into consideration regarding its achievements and limits …

Current therapeutic options and treatments in development for the management of primary open-angle glaucoma.

JM Liebmann, JK Lee - The American journal of managed care, 2017 - europepmc.org
Primary open angle glaucoma (POAG) is the most common type of glaucoma, and is
responsible for approximately 90% of glaucoma cases in North America. POAG is …

Exciting directions in glaucoma

CA Rasmussen, PL Kaufman - Canadian Journal of Ophthalmology, 2014 - Elsevier
Glaucoma is a complex, life-long disease that requires an individualized, multifaceted
approach to treatment. Most patients will be started on topical ocular hypotensive eyedrop …

A highly effective and ultra-long-acting anti-glaucoma drug, with a novel periorbital delivery method

DF Woodward, JW Wang, RA Coleman… - Journal of ocular …, 2019 - liebertpub.com
Purpose: Two features define the future of glaucoma therapeutics:(1) greatly improved
ocular hypotensive efficacy and (2) a delivery method that improves patient convenience …

The efficacy and harm of prostaglandin analogues for IOP reduction in glaucoma patients compared to dorzolamide and brimonidine: a systematic review

WG Hodge, J Lachaine, I Steffensen… - British Journal of …, 2008 - bjo.bmj.com
Aim: To systematically review the literature on the efficacy and harm of prostaglandin
analogues (PGAs) compared to brimonidine and dorzolamide in treating elevated …