Dissecting the expression dynamics of RNA-binding proteins in posttranscriptional regulatory networks

N Mittal, N Roy, MM Babu… - Proceedings of the …, 2009 - National Acad Sciences
In eukaryotic organisms, gene expression requires an additional level of coordination that
links transcriptional and posttranslational processes. Messenger RNAs have traditionally …

Interplay between posttranscriptional and posttranslational interactions of RNA-binding proteins

N Mittal, T Scherrer, AP Gerber, SC Janga - Journal of molecular biology, 2011 - Elsevier
RNA-binding proteins (RBPs) play important roles in the posttranscriptional control of gene
expression. However, our understanding of how RBPs interact with each other at different …

The architecture of the human RNA-binding protein regulatory network

A Quattrone, E Dassi - IScience, 2019 - cell.com
RNA-binding proteins (RBPs) are key players of post-transcriptional regulation of gene
expression, relying on competitive and cooperative interactions to fine-tune their action …

Construction, structure and dynamics of post-transcriptional regulatory network directed by RNA-binding proteins

SC Janga, N Mittal - RNA infrastructure and networks, 2011 - Springer
Gene expression is a highly controlled process which is known to occur at several levels in
eukaryotic organisms. Although messenger RNAs have been traditionally viewed as passive …

Global approaches in studying RNA-binding protein interaction networks

EL Sternburg, FV Karginov - Trends in biochemical sciences, 2020 - cell.com
RNA-binding proteins (RBPs) play crucial roles in almost all aspects of cellular biology. RBP
binding at specific target sites impacts expression of functionally coordinated sets of mRNAs …

Deciphering the role of RNA-binding proteins in the post-transcriptional control of gene expression

S Kishore, S Luber, M Zavolan - Briefings in functional genomics, 2010 - academic.oup.com
Eukaryotic cells express a large variety of ribonucleic acid-(RNA)-binding proteins (RBPs)
with diverse affinity and specificity towards target RNAs that play a crucial role in almost …

Handshakes and fights: the regulatory interplay of RNA-binding proteins

E Dassi - Frontiers in molecular biosciences, 2017 - frontiersin.org
What drives the flow of signals controlling the outcome of post-transcriptional regulation of
gene expression? This regulatory layer, presiding to processes ranging from splicing to …

Deciphering human ribonucleoprotein regulatory networks

N Mukherjee, HH Wessels, S Lebedeva… - Nucleic acids …, 2019 - academic.oup.com
RNA-binding proteins (RBPs) control and coordinate each stage in the life cycle of RNAs.
Although in vivo binding sites of RBPs can now be determined genome-wide, most studies …

From specific to global analysis of posttranscriptional regulation in eukaryotes: posttranscriptional regulatory networks

SC Janga - Briefings in functional genomics, 2012 - academic.oup.com
Regulation of gene expression occurs at several levels in eukaryotic organisms and is a
highly controlled process. Although RNAs have been traditionally viewed as passive …

Post-transcriptional regulatory patterns revealed by protein-RNA interactions

A Zanzoni, L Spinelli, DM Ribeiro, GG Tartaglia… - Scientific Reports, 2019 - nature.com
The coordination of the synthesis of functionally-related proteins can be achieved at the post-
transcriptional level by the action of common regulatory molecules, such as RNA–binding …