Apoptosis induced by modulation in selenium status involves p38 MAPK and ROS: implications in spermatogenesis
P Ranawat, MP Bansal - Molecular and cellular biochemistry, 2009 - Springer
Selenium has been linked to cell survival and apoptosis. Apoptosis plays an important role
in spermatogenesis. Evidence suggests that reactive oxygen species induce apoptotic …
in spermatogenesis. Evidence suggests that reactive oxygen species induce apoptotic …
Dietary selenium variation-induced oxidative stress modulates CDC2/cyclin B1 expression and apoptosis of germ cells in mice testis
N Kaushal, MP Bansal - The Journal of nutritional biochemistry, 2007 - Elsevier
Oxidative stress has been linked with apoptosis in germ cells and with male infertility.
However, the molecular mechanism of oxidative-stress-mediated apoptosis in germ cells …
However, the molecular mechanism of oxidative-stress-mediated apoptosis in germ cells …
Decreased glutathione levels potentiate the apoptotic efficacy of selenium: possible involvement of p38 and JNK MAPKs—in vitro studies
P Ranawat, MP Bansal - Molecular and cellular biochemistry, 2008 - Springer
The present study was designed to evaluate the apoptotic efficacy of selenium (Se) under
glutathione-deprived conditions. Testicular cells were used as a model to assess the above …
glutathione-deprived conditions. Testicular cells were used as a model to assess the above …
Selenium attenuates bisphenol A incurred damage and apoptosis in mice testes by regulating mitogen‐activated protein kinase signalling
Being a vital micronutrient, along with a trace element, selenium (Se) protects the cells from
oxidative stress (OS) in the form of selenoproteins. Bisphenol A (BPA) is a xeno‐oestrogenic …
oxidative stress (OS) in the form of selenoproteins. Bisphenol A (BPA) is a xeno‐oestrogenic …
Selenium variation induced oxidative stress regulates p53 dependent germ cell apoptosis: plausible involvement of HSP70-2
N Kaushal, MP Bansal - European journal of nutrition, 2009 - Springer
Background Selenium at altered concentration causes abnormal spermatogenesis and male
infertility. However, the exact mechanism behind this is still unexplored. Aims It was aimed to …
infertility. However, the exact mechanism behind this is still unexplored. Aims It was aimed to …
Both selenium deficiency and excess impair male reproductive system via inducing oxidative stress-activated PI3K/AKT-mediated apoptosis and cell proliferation …
Z Xu, M Liu, QJ Niu, YX Huang, L Zhao, XG Lei… - Free Radical Biology …, 2023 - Elsevier
Selenium (Se) deficiency or excess impairs testicular development and spermatogenesis,
while the underlying mechanisms in this regard remain unclear. This study was designed to …
while the underlying mechanisms in this regard remain unclear. This study was designed to …
Dietary selenium excess affected spermatogenesis via DNA damage and telomere-related cell senescence and apoptosis in mice
Y Zhang, J Liu, X Li, G Zhou, Y Sang, M Zhang… - Food and Chemical …, 2023 - Elsevier
Selenium (Se) is a vital microelement for spermatogenesis and male fertility. The aim of this
study was to investigate the effects of Se on the male reproductive function and possible …
study was to investigate the effects of Se on the male reproductive function and possible …
Co-operative effect of glutathione depletion and selenium induced oxidative stress on API and NFkB expression in testicular cells in vitro: insights to regulation of …
S Shalini, MP Bansal - Biological research, 2007 - SciELO Chile
Previous studies have shown that transcription factors, API and NFkB exert important roles in
the process by which selenium regulates spermatogenesis. Glutathione, an intracellular …
the process by which selenium regulates spermatogenesis. Glutathione, an intracellular …
Role of selenium in regulation of spermatogenesis: involvement of activator protein 1
S Shalini, MP Bansal - Biofactors, 2005 - Wiley Online Library
Selenium (Se) is involved in the process of male reproduction. Several studies have been
carried out to find the mechanism of Se action through identified selenoproteins. Especially …
carried out to find the mechanism of Se action through identified selenoproteins. Especially …
Differential involvement of reactive oxygen species in apoptosis induced by two classes of selenium compounds in human prostate cancer cells
GX Li, H Hu, C Jiang, T Schuster… - International journal of …, 2007 - Wiley Online Library
Selenium is a promising chemopreventive agent for prostate cancer, possibly via an
induction of apoptosis. Earlier studies have shown that selenite induces DNA single strand …
induction of apoptosis. Earlier studies have shown that selenite induces DNA single strand …