The first closed bilayer phospholipid systems, called liposomes, were described in 1965 and
soon were proposed as drug delivery systems. The pioneering work of countless liposome …

As drug carriers, liposomes have great potential in that selective targeting and release rate
control of drugs can be performed by appropriate modifications to the carrier itself, without …

Introduction: The use of liposomes increases the therapeutic index of many drugs, and also
offers drug targeting and controlled release. The commercial impact of liposomes is …

In the 1980s, the center of entrepreneurial activity for the application of liposome science to
medicine took the form of a company called Vestar Inc.(which became NeXstar …

Liposomal technology has been widely used in the pharmaceutical field for the preparation
of nano-sized drug delivery systems based on natural or synthetic lipids. Liposomes …

Although hydrophilic small molecule drugs are widely used in the clinic, their rapid
clearance, suboptimal biodistribution, low intracellular absorption and toxicity can limit their …

The concept of controlled drug delivery is not new to pharmacology. A considerable amount
of ingenuity has been expended in attempts to alter the pharmacodynamic characteristics of …

Liposomes were the first nanoscale drug to be approved for clinical use in 1995. Since then,
the technology has grown considerably, and pioneering recent work in liposome-based …

The liposomes have continued to be well-recognized as an important nano-sized drug
delivery system with attractive properties, such a characteristic bilayer structure assembling …